Advocate Ramanunni is an MLA of Palakkad who gets expelled from his political communist party, the CDP for assaulting the District Secretary Ambadi Mohanan and joins the rival secularist party, the NSP. Ramanunni, who has been receiving threats from CDP activists, decides to take a gun license for self-protection and this becomes a controversy in the news. Ramanunni's mother Ragini disapproves of his decision to join the NSP as they come from a communist-oriented family and his father Raghavan, a CDP activist who is believed to have been martyred by NSP activists. The NSP decides to appoint Ramanunni as their candidate in the upcoming election. The decision is opposed by Udayabhanu, a veteran politician of the NSP but this is overlooked by the others. Ramanunni, along with his sidekick Thomas Chacko, the NSP Youth Wing Secretary, attend an interview where Mohanan assaults Ramanunni. As the promotions for the elections begin, the CDP announces their candidate as Ragini, who they think is the only person who can defeat Ramanunni. While campaigning at a football match, Mohanan is shot dead and Ramanunni and Chacko become the prime suspects. The Investigation Officer, Paulson Devassy, who is also present at the assassination point, finds out that Ramanunni's gun is missing a bullet. Ballistics match the bullet that killed Mohanan with the bullets in Ramanunni's gun, and shows that the gun must have been fired from the row where Ramanunni and Chacko were sitting. Ramanunni and Chacko escape police custody and hide in the house of V.G. Madhavan, a journalist and a good friend of Ramanunni. Madhavan's daughter Helena decides to help them. Now in disguise, they leave for a resort on an island off the coast of Goa. Unknown to Ramanunni and Chacko, Helena televises all their actions through hidden cameras under the name of 'Hot Pursuit' in order to find the real culprit. With Ramanunni gone, the NSP appoints Sumesh Venjara, a disliked and weak politician as their new candidate. In Goa, Ramanunni reveals that it was Ambadi Mohanan and Udayabhanu who were behind his father's death and not the NSP activists. As the videos get televised, Officer Paulson Devassy gathers evidence of Mohanan's death that leads to Udayabhanu; especially a can of Red Bull that was used as a suppressor since Udayabhanu was very fond of the drink. Police later arrests him. It is revealed that televising Ramanunni's escape was his and Helena's plan to prove his innocence. Ramanunni goes on to win the election as an independent candidate. In a major twist, it turns out that it was actually Ramanunni who had assassinated Ambadi Mohanan with the help of a fellow CDP comrade Chandran. He accused Udayabhanu because of his role in his father's death. He explains to his mother that it was his duty to remove all obstacles from the CDP's path. His mother salutes Ramanunni, and he does the same back.
Ramaleela release was delayed on account of actor Dileep's arrest for conspiracy to kidnap and attempt to rape of an Indian film actress. Despite calls for a boycott, the film released in India on 28 September 2017. It released across 129 screens in Kerala.
Box office
The film grossed 2.13 crore on the opening day from the Kerala box office and collected a total of 10.60 crore in the first 4 days. The film grossed approximately 20.66 crore from 10 days run in the Kerala box office. It grossed 33.2 crore from Kerala in 38 days run. The film grossed 50 crore.
