In 2002, Khan was the co-creator of a blog called Gene Expression; it discussed technical and social issues in genetics. Since writing for Gene Expression, he has written science articles for numerous mainstream publications, and many of the articles touched on controversial subjects such as race, gender, and intelligence. Michael Schulson wrote Khan has written articles for publications associated with the alt-right and his career is an example of the "murky line between mainstream science and scientific racism." Khan's publications have been cited by popular science writers, including his work on the migrations of Southeast Asian Civilizations, Jewish migrations family genetics, and consumer genetics. In 2014, Khan made news when he sequenced his son's genome while still in utero. Antonio Regalado wrote his son may be the first healthy person to have his entire genome sequenced before being born. In an interview with Don Gonyea, Khan stated his child was the most important thing in his life, so it made sense to know everything about his genetics. He was able to obtain the genome sequence by requesting a chorionic villus sampling test. After obtaining the raw genetic data, Khan used the free softwarePromethease to analyze the data. Khan believes society is in the "second age of eugenics," and full genome sequences of fetuses will become standard procedure for parents in the 21st century. Ainsley Newsome wrote "Khan's decision to obtain the whole genome sequence of his partner's fetus while in utero shows us that genomics is no longer a fantasy." In March 2015, the New York Times announced that it hired Khan on a short-term contract, and he will write about once a month for the Times. The Times wrote he is "a science blogger and a doctoral candidate in genomics and genetics at the University of California, Davis. He writes about evolution, genetics, religion, politics and philosophy." The same day the Times announced hiring Khan, Gawker published an opinion piece written by J.K Trotter, who noted that Khan also wrote blogs for Taki's Magazine, a site "founded in 2007 by Taki Theodoracopulos, the flamboyantly racist Greek." As a result of Khan's history of writing for controversial publications, the Times removed him as a regular periodic contributor, but stated they remain "open to consideration of submissions from him" in the op-Ed pages. The Times did not specifically mention the part of Khan's work they found uncomfortable, and he wrote two op-eds for the Times before they ended his contract. Khan wrote on Twitter, "yeah, told me today. may contribute one-off op-eds in future. i’m chill about it. it wasn’t a surprise that ppl went ballistic." In a 2016 interview with the economist and podcaster James Miller, referring to the cancelled Times contract, Khan stated, "I have a clean conscience because I say what I think is true."
Other projects
In December 2010 Khan co-founded the group blogBrown Pundits together with Pakistani-Briton Zachary Latif and Pakistani-American Omar Ali. The blog pertains mainly to South Asian issues. In October 2018 they began an associated podcast called The Brown Pundits Podcast.
Publications
Khan has been a frequent writer with the following publications:
