Regions of Madagascar
is divided into 22 regions. These formerly second-tier administrative divisions became the first-level administrative divisions when the former six provinces were dissolved on 4 October 2009:
| Number on map | Name | Area | Population | Population density per km2 | Capital | Former province |
| 1 | Diana | 19,266 | 889,736 | 36.3 | Antsiranana | Antsiranana |
| 2 | Sava | 25,518 | 1,123,013 | 38.4 | Sambava | Antsiranana |
| 3 | Itasy | 6,993 | 897,962 | 104.8 | Miarinarivo | Antananarivo |
| 4 | Analamanga | 16,911 | 3,618,128 | 198.0 | Antananarivo-Renivohitra | Antananarivo |
| 5 | Vakinankaratra | 16,599 | 2,074,358 | 108.6 | Antsirabe | Antananarivo |
| 6 | Bongolava | 16,688 | 674,474 | 27.4 | Tsiroanomandidy | Antananarivo |
| 7 | Sofia | 50,100 | 1,500,227 | 24.9 | Antsohihy | Mahajanga |
| 8 | Boeny | 31,046 | 931,171 | 25.8 | Mahajanga | Mahajanga |
| 9 | Betsiboka | 30,025 | 394,561 | 9.8 | Maevatanana | Mahajanga |
| 10 | Melaky | 38,852 | 309,805 | 7.5 | Maintirano | Mahajanga |
| 11 | Alaotra-Mangoro | 31,948 | 1,255,514 | 32.1 | Ambatondrazaka | Toamasina |
| 12 | Atsinanana | 21,934 | 1,484,403 | 57.9 | Toamasina | Toamasina |
| 13 | Analanjirofo | 21,930 | 1,152,345 | 47.2 | Fenoarivo Atsinanana | Toamasina |
| 14 | Amoron'i Mania | 16,141 | 833,919 | 44.3 | Ambositra | Fianarantsoa |
| 15 | Matsiatra Ambony | 21,080 | 1,447,296 | 56.9 | Fianarantsoa | Fianarantsoa |
| 16 | Vatovavy-Fitovinany | 19,605 | 1,435,882 | 72.2 | Manakara | Fianarantsoa |
| 17 | Atsimo-Atsinanana | 18,863 | 1,026,674 | 47.6 | Farafangana | Fianarantsoa |
| 18 | Ihorombe | 26,391 | 418,520 | 11.8 | Ihosy | Fianarantsoa |
| 19 | Menabe | 46,121 | 700,577 | 12.8 | Morondava | Toliara |
| 20 | Atsimo-Andrefana | 66,236 | 1,799,088 | 19.9 | Toliara | Toliara |
| 21 | Androy | 19,317 | 903,376 | 38.0 | Ambovombe-Androy | Toliara |
| 22 | Anosy | 25,731 | 809,313 | 26.1 | Tôlanaro | Toliara |