Ribosomal protein L13 leader


L13 ribosomal protein leaders are part of the ribosome biogenesis. They are used as an autoregulatory mechanism to control the concentration of ribosomal proteins L13. An experimentally confirmed ribosomal protein leader autoregulatory structure was found in B. subtilis and other low-GC Gram-positive bacteria. It is located in the 5′ untranslated regions of mRNAs encoding the L13-S9 ribosomal protein operon. A second example were predicted in Bacteroidia with bioinformatic approaches, but the structure of the putative Bacteroidia example is apparently unrelated to the previously established L13 ribosomal protein leader.