At the 1708 British general election, Lumley was returned as Whig MP for East Grinstead. He supported the naturalization of the Palatines in 1709. He wished to serve in the army, and though not given a commission, he joined the Duke of Marlborough for the campaign in the spring and summer of 1709. In 1710, he voted for the impeachment of Dr Sacheverell. He succeeded his recently deceased, elder brother as MP for Arundel at the 1710 British general election. He also became vice-admiral of County Durham in 1710. He voted for the ‘No Peace without Spain’ motion on 7 December 1711. By January 1712 he held an army commission as lieutenant-colonel of horse and became lieutenant-colonel of the 1st Dragoon Guards in 1713. He told against a Court amendment to the Address on 10 April 1713, and voted on against the French commerce bill on 18 June 1713. At the 1713 British general election he was returned again for Arundel. He was concerned about the movements of the Pretender and campaigned for his removal from Lorraine. He spoke and voted against the expulsion of Richard Steele from the House. In 1714 he was appointed Lord of the bedchamber to the Prince of Wales in September 1714 and became Master of the Horse to the Prince of Wales in November 1714. In 1715, Lumley was called to the House of Lords in his father's barony of Lumley. He became colonel and captain of the 1st Foot Guards in 1715 and fought against the Jacobites at the Battle of Preston that year. He remained a Whig supporter in the House of Lords, but in 1717 he was forced to sell his regiment for his adherence to the Prince of Wales. On 2 May 1721 he stood as proxy for Ernest, Duke of York at the baptism of William Augustus. After inheriting his father's titles in December 1721, as Lord Scarbrough, he became Lord Lieutenant of Northumberland and Colonel of the Coldstream Guards in 1722 and was made a Knight of the Garter on 9 July 1724. On the accession of King George II in 1727, he became Master of the Horse to the King and was admitted to the Privy Council on 15 June 1727. He gave up his court post in 1734 and was promoted to major-general in 1735 and lieutenant-general in 1739. In 1739, he was one of the founding governors for the Foundling Hospital in London.
Death and legacy
Lord Scarbrough committed suicide by shooting himself through the roof of the mouth on 29 January 1740, aged 53. At the time of his death it was rumoured to have been brought on by a mental disorder he developed from a knock on the head when he had an accident in his carriage a few days before. There was also a rumour that he had killed himself because of a betrayal of trust. The rumour ran that he had confided a secret of State to the dowager Duchess of Manchester who he had been about to marry, and that she had then told this secret to others. When word got back to the king of the source of the leak of the secret, Scarborough killed himself. Lord Scarborough was buried on 4 February 1740 in Grosvenor Chapel, South Audley Street, Mayfair. Scarborough's titles passed to his brother, Thomas.