Mammone's research interests lie in computational pattern recognition and signal processing. He performed research on Neural networks and signal processing, generating over 15 patents and producing 150 published papers. Mammone started high-tech companies and serves as consultant to government agencies and industry. As an entrepreneur, his interests lie in the processes involved in creating technology products. In supply chain management, Mammone advocates developing product platforms that can be designed within an existing product’s value chain. Groundbreaking corneal mapping technology catalyzed his second venture, Computed Anatomy Inc. The firm was first to develop, manufacture and sell computer aided surgery tools for corneal surgery commonly referred to today as LASIK surgery. His software is still used for laser eye surgical procedures. Computed Anatomy was sold in 1986 to a Japanese manufacturer of ophthalmic tools. In 1992, Mammone founded SpeakEZ Inc., a provider of biometric security systems. The company brought innovative speech recognition technology to market that revolutionized the world of voice activated security systems and voice recognition applications. In 1994, it was sold to T-Netix, a publicly tradedtelecommunications company. During his three-year tenure, Mammone rolled out and managed several successful products. At the height of the dot com era in 2000, Mammone launched The mBook Company. The company developed new media alternatives for textbooks and trade books using technology. Although the firm disbanded in 2001 due to investment related issues, it made strides in developing an interactive e-learning platform at a time when high bandwidth video over the internet was unavailable, garnering support from Cisco and other strategic partners. Currently, Mammone serves as the liaison between Rutgers University and Industry by coordinating networking events, web sites and projects that combine business and technology interests. He directs the CAIP center which provides Cyber infrastructure platforms for academic and nonprofit institutions. Mammone's current interests lie in fostering an ecosystem of innovation and new venture development. To that end, he served as the Director of the Business, Engineering, Science, and Technology Institute which focuses on starting new companies based on university intellectual property. He is a contributor to Business Week, featuring articles that speak to the challenges faced by entrepreneurs. He is currently involved in launching a start-up, myPowerMap LLC, a firm that specializes in developing home energy consumption monitoring technology.