Schmidt completed his A-level examinations in 1953 and graduated from the Neusprachliches Gymnasium in Frankenthal. The same year, he began his medical studies at Heidelberg University which he successfully completed in the winter semester of 1958/59. He obtained his first doctorate in medicine on 22 April 1959 in Heidelberg. After completing a medical internship and surgical residency between 1 May 1959 and 31 October 1960 at Heidelberg University and the Bethanien Hospital in Heidelberg, he completed a second doctoral degree program and was awarded a Ph.D. on 21 March 1963 from the Australian National University in Canberra. He obtained his license to practice medicine from the Baden-Württemberg Ministry of the Interior on 8 August 1963. From 1956 until 1959, he was a doctoral candidate and student assistant at the Heidelberg University Institute of Physiology. From 1960 to 1962, he was a research scholar in the Department of Physiology, Australian National University Canberra, Australia. Subsequently he worked until 1966 as a scientific assistant at the Heidelberg University Institute of General Physiology. On 4 June 1964 he received his habilitation in physiology from the Faculty of Medicine at Heidelberg University. In 1966 he was appointed to the scientific advisory board at the 2nd Institute of Physiology at Heidelberg University and was given lifetime tenure. On 28 January 1970 he was named as an adjunct professor by the Faculty of Medicine at Heidelberg University. From 1970 to 1971 he was a Visiting Research Associate Professor in the department of physiology, State University of New York at Buffalo, N.Y., USA. In 1979 he served as Chairman of the German Physiological Society. From 1971 to 1982 Schmidt worked as professor and director of the Institute of Physiology at Kiel University and from 1982 to 2000 as professor and director of the Institute of Physiology at the University of Würzburg. As of 1 October 2000 he became Emeritus Professor of Physiology at the Faculty of Medicine of the University of Würzburg. In 2001 he was awarded an honorary professorship by the Faculty of Medicine of the University of Tübingen.
Work
Research
From 1956 to 1960 Schmidt’s research was devoted to cardiac electrophysiology and pharmacology. From 1960 to 1970 he studied the mechanisms and functions of presynaptic inhibition in the spinal cord, and since 1965 he has studied somatosympathetic interactions. Between 1970 and 1973, his additional areas of research interest included cerebellar physiology, and from 1972 to 1981, receptor characteristics and central connections in fine muscle afferents, and in 2012, the neurophysiology of nociception and pain, especially in relation to joint pain. His primary research focus has been the characteristics of pain receptors and the processing of signals emanating from them in the spinal cord. Thus, for example, he discovered “sleeping pain receptors” which begin to function only when tissues become inflamed. He also explained the time course and the causes for increased sensitivity of pain receptors in inflamed tissues, such as occurs after sunburn.
Teaching
Schmidt co-edited and personally wrote a number of textbooks, the best known of which is his textbook, Physiologie des Menschen. The book is currently in its 31st edition, and is considered the standard textbook of physiology in German language. Since 2007 Robert F. Schmidt had been taken on a leading role in the development of patient information and communication systems that can be readily understood by laypersons.