Criegee's parents' house was wealthy, his father worked as a court director. The Criegee family was attuned national liberal, Prussian and Protestant, what Rudolf Criegee felt as a great fortune. His happy childhood was ended by the World War I, already in March 1915, his eldest brother died on the Western Front, a second brother was seriously injured in the summer of 1916. Criegee himself was still drafted by end of the war as a young man. After the turmoil of the post-war period and the passed Abitur he matriculated at the University of Tübingen in chemistry in the summer semester 1920. After four semesters of study and moderate success, but the experience from the student fraternity Germania and twelve duels Criegee changed to the University of Greifswald. He remained there for three semesters and passed his first examination, after which he went to the University of Würzburg and received his PhD in December 1925 at Otto Dimroth with a thesis on acridinium salts. The joy about the successful completion was marred by the death of his father in 1926 and also his mother suffered from a serious illness, she died in 1932. Criegee remained in Würzburg and in 1930 he received his habilitation with a thesis on the „Oxydation ungesättigter Kohlenwasserstoffe mit Blei-Salzen“. In 1928, Rudolf Criegee had married his former fellow student Marianne Henze. In 1932 he moved to the University of Marburg, where he was a senior assistant to Hans Meerwein. In November 1933, he was one of the signatories to the Vow of allegiance of the Professors of the German Universities and High-Schools to Adolf Hitler and the National Socialistic State. In 1937 he received an associate professorship at the Technical University of Karlsruhe, but his work was interrupted by the World War II due to the two-time draft for military service again and again. In the summer of 1942, he was seriously wounded on the Eastern Front, his wife also died on February 10. Criegee was released for the research, but the institute was destroyed by bombs in the summer of 1944, and in December he married again. During the rebuilding, he declined several calls to other universities and was appointed a full professor in 1947, from 1949 he led the Institute of Organic Chemistry. Rudolf Criegee continued to refuse all calls to other universities, the new building, in which the institute was located since 1966, originated among his leadership. Even after his retirement in 1969 Criegee carried out research until his death on November 7, 1975. In his scientific work he was primarily involved with oxidation processes of organic compounds, where he used Lead acetate and Osmium tetroxide as Oxidizing agents. A focus was the investigation on the Autoxidation of unsaturatedcyclic Hydrocarbons to Peroxides. One of his great achievements was the elucidation of the reaction mechanism for ozonolysis to form Ozonides The Criegee intermediate and the Criegee rearrangement are named after him. In this context, his research on cyclic reactions and cyclic rearrangement-mechanisms led him, independently of the Nobel Prize–winning work of R.B.Woodward and R.Hoffmann, to the same conclusions as theirs, but he failed to publish his findings in time. In the last years of his scientific work, he investigated the chemistry of small carbon rings, especially Cyclobutadiene and its Derivatives.