Russell attended Creekview High School, where as a senior defensive lineman he registered 62 tackles and 5 sacks, while being named second-team All-district. He accepted a scholarship from Purdue University. His best season came as a freshman, playing as a defensive end in a 4-3 defense, registering 11 starts, 33 tackles, one sack, 3 forced fumbles and 3 fumbles recovered. The next year, he tallied 13 starts, 37 tackles and 4 sacks. As a junior the team switched to a 3–4 defense in mid-October and he was moved to the Jack linebacker position, recording 11 starts, 35 tackles and 2 sacks. In his last year he was moved back to defensive end, replacing the graduated Bruce Gaston. He had 44 tackles and 3 sacks, finishing his career as a four-year starter with 149 tackles and 10 sacks.
Russell was selected by the Dallas Cowboys in the fifth round of the 2015 NFL Draft, after dropping because his physical skills didn't match his on-field production. In training camp he was tried at left defensive end and at the three-technique defensive tackle positions. During the season, he appeared in one game and was declared inactive in 11. After being limited with an abdomen strain, he was placed on the injured reserve list on December 2, in order to activate offensive tackleChaz Green from the reserve/PUP list. In the 2016 training camp, he was given the chance to start after the suspensions to defensive endsDeMarcus Lawrence and Randy Gregory. On September 3, he was released after struggling during the preseason games. The next day, he was signed to the Cowboys' practice squad. He was released on September 6.
On September 21, 2016, Russell was signed to the Tampa Bay Buccaneers' practice squad. He was promoted to the active roster on November 12, and had his first career sack against the Seattle Seahawks. He played in 8 games as a reserve defensive end, collecting 4 tackles and one sack. In 2017, he appeared in 14 games with 7 starts, while registering 17 tackles. He missed the fifth and sixth games with a dislocated left shoulder, which limited him the rest of the year. His 2 sacks came in each of the final two contests. He wasn't re-signed after the season.
Buffalo Bills
On July 29, 2018, Russell signed with the Buffalo Bills. He was released, with thirty-five other teammates, in September 2018 by the Bills to reach the league’s 53-man roster limit. He missed the 2018 season due to a shoulder injury.
Personal life
Following the death of close friend and former teammate Joseph Gilliam in 2018, Russell suffered from a severe bout of depression. He moved to Los Angeles and began writing. In August 2019, he came out publicly as bisexual in an essay for ESPN. He did so to live honestly and without fear of being outed; he also cited the fear of not being able to support his mother and grandfather if he lost his career. At the same time he introduced his boyfriend Corey O’Brien, a dancer; they opened Corey & Russ, a YouTube channel; as of June 2020, they have over 15,600 followers. If Russell were to sign with an NFL team, he would be the only athlete in the four American major professional sports leagues to openly identify as LGBTQ. A former NFL offensive linemanRyan O'Callaghan, who came out as gay after he left the league, said that as of August 2019 every NFL team had at least one closeted gay or bisexual player. Sarah McBride, national Press Secretary for Human Rights Campaign, praised Russell for "creating more space and opportunity for young LGBTQ people to dream big and to pursue their goals".
