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S-18986
S-18986
is a
positive allosteric modulator
of the
AMPA receptor
related to
cyclothiazide
. It has
nootropic
and
neuroprotective
effects
in
animal studies
, and
induces
both
production
of
BDNF
and AMPA-mediated
release
of
noradrenaline
and
acetylcholine
in the
hippocampus
and
frontal cortex
of
the brain
.