SUMO3


Small ubiquitin-related modifier 3 is a protein that in humans is encoded by the SUMO3 gene.

Function

SUMO proteins, such as SUMO3, and ubiquitin posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability.

Interactions

SUMO3 has been shown to interact with ARNTL and Thymine-DNA glycosylase.