An accomplished stage actor, he has appeared on Broadway and in regional theaters including San Francisco's American Conservatory Theater and Berkeley Repertory Theatre. He was cast as Ito opposite Angela Lansbury's Auntie Mame in Jerry Herman's Broadway musical hit Mame in 1966. This was followed by Lovely Ladies, Kind Gentlemen, The Chickencoop Chinaman, and the role of Manjiro in Stephen Sondheim & Harold Prince's Pacific Overtures – he would go on to play Lord Abe in the 2004 Broadway revival. He was in the short lived 1978 musical Barbary Coast, and was nominated for a Drama Desk Award for Outstanding Actor in a Play for his leading performance in Philip Kan Gotanda's The Wash. In 2010, he appeared in the world premiere of No-No Boy by Ken Narasaki based on the novel by John Okada. He is closely affiliated with the East West Players and South Coast Repertory companies, most recently starring in a run of Julia Cho's Aubergine. His more memorable film roles include Saito in the 1986 comedy Gung Ho, Hiroshi Kawamura in the 1990 drama Come See the Paradise, the coroner "Painless" Kumagai in 1990's Presumed Innocent, Dr. Max Shinoda in 1993's Suture, Lord Norinaga in 1993's Teenage Mutant Ninja Turtles III, and in Old Dogs, alongside John Travolta and Robin Williams, as Japanese billionaire Yoshiro Nishamura. He played Dr. Tam in the 1994 filmThe Shadow. He can also be seen in Asian Americanindependent filmsAmericanese, The Sensei and Life Tastes Good. Shimono performed the voice of Subotai in the 1982 film Conan the Barbarian, dubbing actor Gerry Lopez. On television, he starred on the 2008 ABC family miniseries Samurai Girl. Then Shimono provided the voices of antique-shop owner/Chi Wizard Uncle Chanon the television series Jackie Chan Adventures, the elderly version of the Emperor on Samurai Jack, Airbending Master Monk Gyatso and Master Yu on the popular series , Mister Sparkle and Master Sushi Chef on The Simpsons and Mr. Murakami on 2012's Teenage Mutant Ninja Turtles series. He also appeared in Royal Pains, season 3 episode "But There's a Catch", as Jono the gardener. In 2007, he appeared in the episode "Don't Worry, Speed Racer" on Two and a Half Men. In 1991 he had a role in the TV movie/pilot Plymouth, which at the time was considered to be one of the most expensive such movies ever made. He also had several appearances in the television showM*A*S*H. Shimono is a cohost of APM Reports podcast . He also tells his personal story in the titled "Sab Shimono Remembers Camp".
Personal life
Shimono is openly gay, and has been in a relationship with writer Steve Alden Nelson since 2001. The couple registered their domestic partnership in April 2005 and married in San Diego on June 23, 2008.