Sclerosis (medicine)

• Amyotrophic lateral sclerosis, sometimes known as Lou Gehrig's disease, a progressive, incurable, usually fatal disease of motor neurons.
• Atherosclerosis, a deposit of fatty materials, such as cholesterol, in the arteries which causes hardening.
• Focal segmental glomerulosclerosis is a disease that attacks the kidney's filtering system causing serious scarring and thus a cause of nephrotic syndrome in children and adolescents, as well as an important cause of kidney failure in adults.
• Hippocampal sclerosis, a brain damage often seen in individuals with temporal lobe epilepsy.
• Lichen sclerosus, an autoimmune disease that hardens the connective tissues of the vagina and the penis.
• Multiple sclerosis, or focal sclerosis, is a central nervous system disease which affects coordination.
• Osteosclerosis, a condition where the bone density is significantly increased, resulting in decreased lucency on radiographs.
• Otosclerosis, a disease of the ears.
• Systemic sclerosis, a rare, chronic disease which affects the skin, and in some cases also blood vessels and internal organs.
• Tuberous sclerosis, a rare genetic disease which affects multiple systems.
• Primary sclerosing cholangitis, a hardening of the bile duct by scarring and repeated inflammation.
• Primary lateral sclerosis, progressive muscle weakness in the voluntary muscles.