Harris received a medical degree from the University of Virginia in 1894 and established a medical practice in Union Springs, Alabama. After the completion of postgraduate studies at Johns Hopkins University, Dr. Harris accepted the position of Professor of Clinical Medicine at the Medical College of Alabama in Mobile. During World War I, Harris was commissioned as a major in the Medical Corps of the U.S. Army and served with distinction. Returning to private practice in Birmingham, Dr. Harris was instrumental in building the 50-bed Gorgas Hospital Hotel which later became Montclair Baptist Medical Center. A prolific author and contributor to medical literature, he advocated a national Department of Health, improved nutrition, and attention to diabetes mellitus. He was instrumental in establishing a camp near Mobile for children with diabetes. In tribute to his life and work, it was later designated Camp Seale Harris. He opened the Seale Harris Clinic in Birmingham in 1922. The clinic and name are perpetuated by his successors. Shortly after the discovery of insulin in 1922, Harris visited Canada to study diabetes cases with the scientists who discovered the hormone. These studies led to research on the effects in nondiabetic patients of an excessive secretion of insulin and his recognition that hyperinsulinism could cause hypoglycemia, a deficiency of sugar in the blood. His research on hyperinsulinism and its control brought international recognition to Harris, including the Distinguished Service Medal, the highest scientific award of the American Medical Association. While serving in the Army during World War I, he edited the journal War Medicine, published in Paris. For 12 years he was the owner and editor of the Southern Medical Journal. His writings include more than 100 contributions to the medical literature and books in such diverse fields as clinical practice, biography and politics. Widely respected among doctors, Harris served at as president of the Southern Medical Association, Medical Association of the State of Alabama, and the American Medical Editors Association.
Harris' syndrome
Harris' syndrome is a historical term for hyperinsulinemic hypoglycemia, such as that caused by insulin-producing tumors of the pancreas. The syndrome is characterized by the symptoms of low blood sugar: weakness, hunger, shakiness, increasing nervousness, mild mental confusion or even personality alterations with erratic behaviour, and the adrenergic responses of tachycardia, pallor, and sweating. The concept of the syndrome was postulated by Harris, in 1924, after he observed hypoglycemia produced during treatment of diabetic patients with the newly discovered insulin. The reception of Harris’s findings were recounted by William Dufty: Seale Harris was awarded the 1949 Distinguished Service Medal of the American Medical Association. Harris was posthumously elected in 1965 to the Alabama Hall of Fame. Dr. Stephen Gyland of Tampa, Florida, suffered from hyperinsulinism and happened on Harris's article in the Journal of the American Medical Association. He wrote a letter to the Journal praising Harris and describing his long search for a diagnosis and treatment before finding Harris's study.
Military career
With the advent of World War I, and with a commission of major in the Medical Corps of the U.S. Army, Dr. Harris was assigned to the staff of generalWilliam Crawford Gorgas. While serving overseas he was decorated for meritorious service by general John J. Pershing.
Seale Harris Award
This award, named in honor of Seale Harris and established in 1958 at the Southern Medical Association meeting in New Orleans, is presented annually to a member of the Southern Medical Association in recognition of important research accomplishments in the broad field of metabolism, endocrinology, or nutrition, or for significant accomplishments contributing to a better understanding of the chemical changes occurring in disease.