Sedation


Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure. Examples of drugs which can be used for sedation include isoflurane, diethyl ether, propofol, etomidate, ketamine, pentobarbital, lorazepam and midazolam.

Medical uses

Sedation is typically used in minor surgical procedures such as endoscopy, vasectomy, or dentistry and for reconstructive surgery, some cosmetic surgeries, removal of wisdom teeth, or for high-anxiety patients. Sedation methods in dentistry include inhalation sedation, oral sedation, and intravenous sedation. Inhalation sedation is also sometimes referred to as relative analgesia.
Sedation is also used extensively in the intensive care unit so that patients who are being ventilated tolerate having an endotracheal tube in their trachea. Also can be used during a long term brain EEG to help patient relax.

Risks

There are studies claiming that sedation accounts for 40 percent to 50 percent procedure-related complications, that is why this process has attracted attention. Airway obstruction, apnea and hypotension are not uncommon during sedation and require the presence of health professionals who are suitably trained to detect and manage these problems. Aside from the suppression of respiration, risks also include unintended levels of sedation, postoperative somnolence, aspiration, and adverse reactions to sedation medications. Complications could also include perforation, bleeding, and the stimulation of vasovagal reflexes. To avoid sedation risks, care providers conduct a thorough pre-sedation evaluation and this process includes pre-sedation history and physicals with emphasis on the determining characteristics that indicate potential risks to the patient and potential difficult airway management. This process can also reveal if the sedation period needs to be prolonged or additional therapeutic procedures are required.

Levels of sedation

Sedation scales are used in medical situations in conjunction with a medical history in assessing the applicable degree of sedation in patients in order to avoid under-sedation and over-sedation.
Examples of sedation scales include MSAT, UMSS, the Ramsay Scale and the RASS.
The American Society of Anesthesiologists defines the continuum of sedation as follows:
In the United Kingdom, deep sedation is considered to be a part of the spectrum of general anesthesia, as opposed to conscious sedation.

Patient screening process

Prior to any oral sedation methods being used on a patient, screening must be done to identify possible health concerns. Before using sedation, doctors try to identify any of the following that may apply: known drug allergies and sensitivities, hypertension, heart defects, kidney disease, other allergens, such as latex allergy, history of stroke or transient ischemic attack , neuromuscular disorders, or a current list of medications and herbal supplements taken by the patient. A patient with any of these conditions must be evaluated for special procedures to minimize the risk of patient injury due to the sedation method.
In addition to the aforementioned precautions, patients should be interviewed to determine if they have any other condition that may lead to complications while undergoing treatment. Any head, neck, or spinal cord injuries should be noted as well as any diagnosis of osteoporosis.

Intravenous Sedation

The most common standard conscious sedation technique for adults is intravenous sedation using Midazolam. This requires a needle to be put into a vein to deliver the medication, this is known as an IV cannula.
Indications:
Contraindications: