Itagaki entered the Imperial Japanese Army Academy, where he befriended numerous notable Japanese military figures including Yasuji Okamura, Kenji Doihara, and Tetsuzan Nagata. Itagaki graduated from the Army Academy in 1904 and fought in the Russo-Japanese War. Itagaki married Kikuko Ogoshi, the daughter of his former mentor Kenkichi Ogoshi who died in the Battle of Mukden. From 1924 to 1926, Itagaki was a military attaché assigned to the Japanese embassy in China. On his return to Japan, he held a number of staff positions within the Imperial Japanese Army General Staff until 1927 before being given a field command as commanding officer of the IJA 33rd Infantry Brigade based in China. His brigade was attached to the IJA 10th Division from 1927 to 1928. Itagaki was then transferred to command the IJA 33rd Infantry Regiment in China from 1928 to 1929, under the aegis of the prestigious Kwantung Army. In 1931, Itagaki rose to become Chief of the Intelligence Section of the Kwantung Army, in which capacity he helped plan the 1931 Mukden Incident that led to the Japanese seizure of Manchuria. Itagaki was subsequently a military advisor to the Japanese puppet state of Manchukuo from 1932 to 1934. In 1934, Itagaki became Vice Chief of Staff of the Kwantung Army, and in 1936 was promoted to Chief of Staff. From 1937 to 1938, Itagaki was commander of the IJA 5th Division in China during the early stages of the Second Sino-Japanese War, and his division took a leading part in the Battle of Beiping–Tianjin, Operation Chahar, and the Battle of Taiyuan. However, in the Battle of Xuzhou his forces were repulsed during the Battle of Taierzhuang in the vicinity of Linyi that prevented them from coming to the aid of Rensuke Isogai's IJA 10th Division. Itagaki was recalled to Japan in 1938, briefly serving as War Minister from 1938 to 1939. On 6 December 1938, Itagaki proposed a national policy in accordance with Hakko Ichiu at the Five Ministers Conference, which was the Japanese highest decision making council, and the council made a decision of prohibiting the expulsion of the Jews in Japan, Manchuria, and China as Japanese national policy. Itagaki returned to China again as chief of staff of the China Expeditionary Army from 1939 to 1941. However, in the summer of 1939, the unexpected defeat of Japanese forces against the Soviet Union at the Battle of Khalkhin Gol, the decisive battle of the Soviet–Japanese border conflicts, was a major blow to his career. Itagaki was reassigned to command the Chosen Army in Korea, then considered to be a non-prestigious backwater post. As the war situation continued to deteriorate for Japan, the Chosen Army was elevated to the Japanese Seventeenth Area Army in 1945, with Itagaki still as commander in chief. Itagaki was then reassigned to the Japanese Seventh Area Army in Singapore and Malaya in April 1945. Itagaki surrendered Japanese forces in Southeast Asia to British AdmiralLouis Mountbatten in Singapore on 12 September 1945.
Death
After the war, Itagaki was taken into custody by the Supreme Commander of the Allied Powers authorities and charged with war crimes, specifically in connection with the Japanese seizure of Manchuria, his escalation of the war against the Allies during his term as War Minister, and for allowing inhumane treatment of prisoners of war during his term as commander of Japanese forces in Southeast Asia. Itagaki was found guilty on counts 1, 27, 29, 31, 32, 35, 36 and 54 and was condemned to death in 1948 by the InternationalMilitary Tribunal for the Far East. Itagaki was hanged on 23 December 1948 at Sugamo Prison in Tokyo.