The college was established as the Ummah Medical College in 1994-95 in Mirpur, Dhaka. It later shifted its premises to this site in 1998 under the current name Shaheed Monsur Ali Medical College and Hospital. It was and is named after Shaheed M Monsur Ali, the 3rd Prime Minister of Bangladesh, and as the Finance Minister of the Mujibnagar Government he was a leader of Bangladesh's 1971 Liberation War as well. It was renamed in 2002 as the Moulana Bhasani Medical College under the Moulana Bhasani Trust. In October 2007, the college shifted to its own building, which was inaugurated by the ex-chairman of the Moulana Bhasani Trust. In February 2009, Dr. Jamal Uddin Chowdhury was elected as chairman of the Moulana Bhasani Trust, later Mrs.Laila Arjumand was elected as Chairman of Moulana Bhasani Trust and Dr. Jamal Uddin Chowdhury was elected as Chairman of Shaheed Monsur Ali Medical College. The institution was renamed to its current name of Shaheed Monsur Ali Medical College on April 3, 2010, in the presence of the Chairman of the Moulana Bhasani Trust Mrs.Laila Arjumand.
Shaheed Monsur Ali Medical College's main campus in Uttara Model Town covers 3 acres. The academic building of the college is built on its own land having spacious classrooms, lecture galleries, practical classrooms, departmental museums, library, s etc. It also accommodates a cafeteria and separate common rooms for male and female students having facilities for indoor games. There are separate hostels for boys and girls. Students have facilities for outdoor games also. The entire library is covered by high speed WIFI internet. The river ‘Turag’ flows beside the campus of the college adding an unlimited fervor to the scenic beauty. It has a 750-bedded hospital with all modern amenities offering emergency, outdoor and indoor services round the clock. The college was approved by the government of Bangladesh. It is affiliated with Dhaka University, and enjoys the recognition of the Bangladesh Medical and Dental Council as well as the World Health Organization. The College also has the recognition of postgraduate training in various subjects in the college hospital by the Bangladesh College of Physicians and Surgeons.
The college has admitted 24 batches of students since its inception. 19 batches of students have completed their MBBS course. The hospital is situated just beside the college building.
Teaching media
Overhead projector, epidiascope, multimedia projector and other audio visual equipments using desktop and laptop. Seminars and symposiums are organized on regular basis to ensure the acquaintances of students with the latest development in medical science.
Teaching methodology
The students will be taught by lectures, clinical demonstrations, tutorials and practical. Ward demonstration, Seminars, Symposiums, workshops, field visit, and Residential Field Side Training, demonstration and autopsy. Student's result will depend on their performance on each item. Regular assessment of the student is done as per university, BMDC and government criteria.