Ikramullah was born as Shaista Akhtar Banu Suhrawardy. Her mother was Nawab Abdul Latif's granddaughter, and her father was Hassan Suhrawardy. She studied at Loreto College, Kolkata. She was also the first Muslim woman to earn a PhD from the University of London. Her doctorate thesis, "Development of the Urdu Novel and Short Story", was a critical survey of Urdu literature.
After she was married, she was one of the first Indian Muslim women in her generation to leave purdah. Muhammad Ali Jinnah inspired her to be involved in politics. She was a leader in the Muslim Women Student's Federation and the All-India Muslim League's Women's Sub-Committee. In 1945, she was asked by the Government of India to attend the Pacific Relations Conference. Jinnah convinced her not to accept the offer, as he wanted her to go as the representative of the Muslim League and to speak on its behalf. She was elected to the Constituent Assembly of India in 1946, but never took the seat, as Muslim League politicians did not. She was one of two female representatives at the first Constituent Assembly of Pakistan in 1947. She was also a delegate to the United Nations, and worked on the Universal Declaration of Human Rights and the Convention Against Genocide. She was Pakistan's Ambassador to Morocco from 1964 to 1967.
Publications
She wrote for Tehzeeb-e-Niswan and Ismat, both Urdu women's magazines, and later wrote for English-language newspapers. In 1950 her collection of short stories, called Koshish-e-Natamaam, was published. In 1951 her book Letters to Neena was published; it is a collection of ten open letters supposedly written to Indians, who are personified as a woman called Neena. The real Neena was one of her in-laws. After the Partition of India, she wrote about Islam for the government, and those essays were eventually published as Beyond the Veil. Her autobiography, From Purdah to Parliament, is her best-known writing; she translated it into Urdu to make it more accessible. In 1991 her book Huseyn Shaheed Suhrawardy: A Biography, about her uncle, was published. She also was one of the eight writers of the book Common Heritage, about India and Pakistan. In her last days, she completed an English translation of Mirat ul Uroos and an Urdu volume on Kahavat aur Mahavray. In 2005 her collection of women's sayings and idioms in Urdu, called Dilli ki khavatin ki kahavatain aur muhavare, was posthumously published. She also wrote Safarnama, in Urdu.