Shankar Balasubramanian


Sir Shankar Balasubramanian is an Indian-born British chemist and Herchel Smith Professor of Medicinal Chemistry in the Department of Chemistry at the University of Cambridge, Senior Group Leader at the Cancer Research UK Cambridge Institute and Fellow of Trinity College, Cambridge. He is recognised for his contributions in the field of nucleic acids. He is scientific founder of Solexa and Cambridge Epigenetix.

Education

Born in Madras India in 1966, Shankar Balasubramanian moved to the UK with his parents in 1967. He grew up in a rural area just outside Runcorn in Cheshire and attended Daresbury Primary School, then Appleton Hall High School. He then went on to study the Natural Sciences Tripos at Fitzwilliam College, Cambridge, where he did his undergraduate degree from 1985–88 and continued with a PhD for research on the reaction mechanism of the enzyme chorismate synthase supervised by Chris Abell.

Career and research

Following his PhD, Balasubramanian travelled to the USA as a SERC/NATO Research Fellow and worked in the group of Stephen J. Benkovic at Pennsylvania State University. He started his independent academic career in 1994 in the University of Cambridge and has remained there ever since, first as College Lecturer, then University Lecturer, University Reader in Chemical Biology and Professor of Chemical Biology. He was most recently appointed Herchel Smith Professor of Medicinal Chemistry in 2008. He currently directs research laboratories in the Department of Chemistry and also the Cancer Research UK Cambridge Institute at the Cambridge Biomedical Campus. His former doctoral students include Julian Huppert.
Balasubramanian works in the field of nucleic acids. His citation on election to the Royal Society reads:
More recently Balasubramanian has been inventing and applying new chemical methods to study epigenetic changes to DNA bases including single base resolution sequencing of 5-formylcytosine, 5-hydroxymethylcytosine and 5-methylcytosine.

Honours and awards

Honours and awards include: