Hari Prasad, a blind flutist lives along with his younger sister in a village near Jaipur, which was also a tourist attraction. Though he lacks knowledge of classical music, he plays flute beautifully and makes a living by playing it to tourists. One day, guide Jyothirmai comes there along with a bunch of tourists and listens to his flute. She understands his talent and helps him understand nature and to become a famous flutist. Years pass and Hari Prasad becomes Pandit Hari Prasad. Unknown to her, Hari Prasad admires her very much and dedicates all his albums to her. Meanwhile, a mute painter Subhashini who meets him in his village, falls for him. Subhashini expresses her feelings through her paintings and gradually her brother understands her feelings regarding Hari Prasad. He approaches Hari Prasad's uncle with a marriage proposal. But at the same time Hari Prasad reveals his admiration for Jyothirmai. This shocks Jyothirmai as she previously worked as an escort to rich tourists. She tries to hint Hari Prasad about her not so decent past, but is overwhelmed by his pure love and disregard for her external characters. Though she herself admires him, she feels that she would taint him with her impure past. She tells Hari Prasad that she couldn't marry him as she already engaged to a doctor. Hari Prasad takes it well as he always wanted Jyothirmai to be happy. On the wedding day, Jyothirmai commits suicide and requests in her last note that her eyes should be donated to Hari Prasad. She also requests that her funeral procession should appear like a marriage procession and her death should be hidden from Hari Prasad. Everyone tries to act normal and sends her as they are sending a bride to her in-laws. Hari Prasad keeps calm all the time and at last goes to the graveyard to say his final goodbyes to Jyothirmai. He tells shocked Subhashini that it's impossible to hide the death of his angel from him. The film ends with Hari Prasad and Subhashini mourning silently in the graveyard.
Sirivennela abounds in classical music composed by K. V. Mahadevan with flute renditions by the renowned flautistHariprasad Chaurasia. The movie saw the debut of Sirivennela Sitaramasastri as a lyricist, who wrote all of the songs. Because of "the wonderful songs," rich in meaning, he penned for the movie, Sitarama Sastry has taken the name Sirivennela. Each of the songs is remembered to this day. The song "Vidhata Thalapuna", sung by S. P. Balasubrahmanyam and P. Susheela, is about Aum, the most sacred syllable in Hinduism, from which the Veda traditions originated. Other notable songs include "Adibhikshuvu Vadinedi Koredhi" and "Ee gali Ee Nela."