The monastery is thought to have been built in 1224 or 1225. It was once enclosed by a circular wall which is today only partly preserved. Its double apse makes it unique in its genre, and some researchers have advanced the hypothesis that this was due to the monastery being used by two religious rites.. The East–West Schism of 1054 appears not to have deterred the Catholic and Orthodox believers in Mesopotam, evidently successful in finding a compromise that enabled them to work together in the construction of the monastery. It is designated as a Cultural Monument of Albania and is a protected heritage site, although the church and temple building is in need of restoration, held against collapse with wooden props and scaffolding. The Orthodox monastery was built on the walls of a much older temple. An Albanian Heritage Foundation team, directed by architect Reshat Gega, conducted research on the monastery, performing excavations and restoration over a period of 20 years. Evidence the team found included Hellenic stones from the 3rd-4th centuries BC, confirming the connection with the capital of the Epirote League at Phoenice located 3 km from the monastery. One of the decorative stones bears the inscription "Menelau", presumed to be a reference to the Spartan KingMenelaus whose brother Agamemnon led the assault during the Trojan War. The nearby area includes the ancient site of Buthrotum which the Roman writer Virgil says was founded by Trojan descendants of Priam, who settled in the area after the Trojan War. The original openings in the temple walls have been used as either alcoves or windows by the builders of the monastery. An accompanying photograph shows such an alcove with an icon of the Saint Nicholas, the patron saint of the monastery.
As is immediately evident to speakers of Greek, Albanian and English, the Greek "Agios Nikolaos" and the Albanian "Shën Kollit" are the same saint, anglicised to Saint Nicholas. Saint Nicholas was contemporary with Saint Spyridon, the patron saint of the island of Corfu, that lies 20 km west of Mesopotam. Bishops Nicholas and Spyridon both attended the First Council of Nicaea in the year 325. The bodies of both saints were "rescued" and sent by ship to Italy during the Fall of Constantinople in 1453. The Corfiots successfully petitioned for the body of Saint Spyridon to be relocated to the capital of Corfu. The remains of Saint Nicholas are revered at Bari's great Basilica di San Nicola Italy, in Venice and at Myra in Turkey.
The temple walls contain several legendary icons including a lion, a serpent dragon with a knot in its tail, and a serpent dragon with its tail coiled around its neck and back.
Access to the Site
The monastery site is normally closed with fencing and locked gates, but the Papas of the modern Orthodoxchurch in Mespotam has the keys and visits can be arranged if planned and coordinated in advance. In May each year the community of Mesopotam village hold an "open day" and "festival" to celebrate Saint Nicholas's "saint's day" at the site of the monastery.