List of highways numbered 181

Canada

• Prince Edward Island Route 181

  Chile

• Route 181-CH in Araucanía Region

  India

• National Highway 181

  Ireland

• R181 road

  Japan

• Japan National Route 181

  United Kingdom

• M181 motorway

  United States

• Interstate 181
• U.S. Route 181
• Alabama State Route 181
• Arizona State Route 181
• Arkansas Highway 181
• California State Route 181
• Connecticut Route 181
• Florida State Road 181
• Georgia State Route 181
• Georgia State Route 181
• Illinois Route 181
• Iowa Highway 181
• K-181
• Kentucky Route 181
• Louisiana Highway 181
• Maine State Route 181
• Maryland Route 181
• Massachusetts Route 181
• M-181
• Missouri Route 181
• New Jersey Route 181
• New Mexico State Road 181
• New York State Route 181
• North Carolina Highway 181
• Ohio State Route 181
• Pennsylvania Route 181
• South Carolina Highway 181
• Tennessee State Route 181
• Utah State Route 181
• Texas State Highway 181
• * Texas State Highway Loop 181
• * Farm to Market Road 181
• Virginia State Route 181
• Washington State Route 181
• Wisconsin Highway 181

• Puerto Rico Highway 181