Seneff attended the Massachusetts Institute of Technology, earning her bachelor of science in biophysics in 1968, a master's in electrical engineering in 1980, and a doctoral degree in computer science in 1985. She is a senior research scientist at the MIT Computer Science and Artificial Intelligence Laboratory. Her research career focused on using computational modeling and analysis of the human auditory system to improve communication between humans and computers. She was elected a Fellow of the International Speech and Communication Association in 2012 as recognition for her "contributions to conversational human-computer systems and computer-assisted language learning". Seneff collaborates with and is married to MIT professor Victor Zue.
Biology and medical topics
In 2011, Seneff began publishing articles on topics related to biology and medicine in low-impact, open access journals, such as Interdisciplinary Toxicology and eight papers in the journal Entropy between 2011 and 2015. According to food columnist Ari LeVaux, Seneff's work in this area has made her "a controversial figure in the scientific community" and she has received "heated objections from experts in most every field she's delved into". In 2013, she coauthored a paper that associated the herbicide glyphosate with a wide variety of diseases such as cancer and disorders such as autism. Discover magazine writer Keith Kloor criticized the uncritical republication of the study's results by other media outlets. Jerry Steiner, the executive vice president of sustainability at Monsanto, said in an interview regarding the study that "We are very confident in the long track record that glyphosate has. It has been very, very extensively studied." Seneff's claim that glyphosate is a major cause of autism and that, "At today's rates, by 2025, half the kids born will be diagnosed with autism," has also been criticized. For example, Pacific Standard noted that, contrary to Seneff's claims, many scientific reviews have found that the rise in autism rates over the past 20 years is due to changes in diagnostic practices, and that a number of studies, including a 2012 review in the Journal of Toxicology and Environmental Health, have found little evidence that glyphosate is associated with adverse development outcomes. Seneff and her MIT colleagues have also published on the health impacts of fat and cholesterol consumption in America. Based on this work, Seneff claimed that Americans are suffering from a cholesterol deficiency, not an excess. In 2014–2016 Seneff was proposed as an expert witness for litigators seeking damages from Pfizer associated with their cholesterol drug Lipitor, but the court dismissed the claim largely because Seneff lacked expert status and failed to provide credible evidence linking Lipitor to any specific harm.
Response from scientists and academics
Clinical neurologist and skeptic Steven Novella criticized Seneff's Entropy publication for making "correlation is causation" assumptions using broad statistical extrapolations from limited data, saying "she has published only speculations and gives many presentations, but has not created any new data". Scientists and scholars such as Derek Lowe, a medicinal chemist, and Jeffrey Beall, a library scientist known for his criticism of predatory open access publishers, have separately criticized Seneff's paper for misrepresenting the results and conclusions of other researchers' work. Lowe and Beall also noted that Entropy and its publisher, MDPI, have a known history of publishing studies without merit. A 2017 Review Article written by Kings College of London researchers and published by Frontiers in Public Health called Seneff's glyphosate health-risk research claims "a deductive reasoning approach based on syllogism" and "at best unsubstantiated theories, speculations or simply incorrect." Consumers Union senior scientist Michael Hansen characterized Seneff and her glyphosate claims as "nutty", "truly unhinged", and "dangerous".
