In 1992, Lowden ran for the Nevada State Senate in Clark County District 3, that usually elects members of the Democratic Party. She defeated longtime incumbent Jack Vergiels, who was then serving as the Nevada Senate Majority Leader. In the Nevada Legislature, Lowden served as the Senate Majority Whip and the Chairman of the Senate Taxation Committee. Her work in office earned her the Guardian of Small Business Award from the Nevada chapter of the National Federation of Independent Business, Senator of the Year Award from the Clark County Republican Party, the Woman of the Year Award from the Republican Women of Las Vegas, and the Lifetime Achievement Award in 2008 from the Republican Women of Henderson. The Culinary Workers Union representing hotel workers, then the most powerful labor force in Las Vegas, has criticized her for her votes to reform the State Industrial Insurance System and because her casino fought efforts by workers to organize there. She said the union harassed her by picketing her home and threatened her to the point where she had to transfer her children to another school. In 1996, she lost a re-election bid to Democrat Valerie Wiener, while most other incumbents held their seats. In 2007 she became Chairwoman of the Nevada Republican Party and held that position until 2009.
2010 U.S. Senate run
On October 1, 2009, Lowden announced her bid for the Republican nomination for US Senate. Her main opponents in the Republican primary were businessman Danny Tarkanian and former State Assemblywoman Sharron Angle. Had Lowden won the Republican primary, she would have run against U.S. Senator Harry Reid, the Senate Majority Leader. She earned endorsements from Rush Limbaugh, Sean Hannity, Jeri Thompson, the Susan B. Anthony List, and former Nevada Governor Robert List. Politico named Lowden's campaign one of "the worst" of 2010 stating "if Senate Majority Leader Harry Reid wins re-election in Nevada, it will likely be thanks to those 14 words spoken by Republican challenger Sue Lowden", referring to Lowden's statement regarding "bringing a chicken to a doctor." Politico also cited controversy over Lowden's use of a campaign supporter's RV, and "an inept response to a question about the Civil Rights Act" as reasons. Tarkanian was her closest primary opponent in two surveys conducted as of April 2010, but polling after Lowden's infamous suggestion that people use the barter system to lower their health care costs showed Angle moving to first place. In general election polling, she once held the largest lead against Reid in aggregate polling conducted as of April 2010. But later May polls showed Lowden losing to Harry Reid by 5 percentage points. In primary election polling, Lowden held an even greater lead of 18 points over her closest primary opponent in two independent surveys conducted April 2010. Her numbers then declined by more than 20 points. Using data from a poll conducted by Mason-Dixon Polling & Research Inc.. the Las Vegas Review-Journal on May 28, 2010 stated that "Republican Sue Lowden has the best chance of defeating U.S. Sen. Harry Reid". The poll predicted that Lowden would win 42 percent of the vote over Reid's 39 percent with a margin of error "plus or minus 4 percentage points." Sharron Angle went on to defeat Lowden by a margin of 13.98%.
2014 election
Lowden confirmed with Nevada political pundit Jon Ralston that she was mulling a run for Nevada Lieutenant Governor in 2014. Ultimately, she lost the primary election to State Senator Mark Hutchison by nearly 18% of the vote.
Personal life
In 1983, she married Paul Lowden, a Nevada businessman. At the time, he owned the Sahara and Hacienda casinos. They later built the Santa Fe Station casino and remain majority owners of the Pioneer Hotel & Gambling Hall. He had a boy and girl, and together they had two sons, and have one granddaughter. She and her husband reside in Las Vegas. In 2016, Chris Lowden, son of Sue Lowden was sued by investors of Stoney's Rockin Country for fraud and racketeering. The Stoney' Rockin Country trademark is currently owned by Archon Corporation, which Sue Lowden sits on the board, owns majority of the company stock, and serves an executive position.
Appearance in media
Lowden had an impromptu appearance on The Tonight Show in 1978 where she was picked out of the audience by guest host Don Rickles who fawned on her as a result of her physical beauty. Rickles was struck by her beauty and joked towards the end of their discussion, "you've got a great a body, I'm not saying that in any kind of sexy way...I want to be with you so bad Sue!" Sue was accompanied by two acquaintances one of which was former professional NFL football player Edgar Chandler.