Sup45p


Sup45p is the Saccharomyces cerevisiae eukaryotic translation termination factor. More specifically, it is the yeast eukaryotic release factor 1. Its job is to recognize stop codons in RNA and bind to them. It binds to the Sup35p protein and then takes on the shape of a tRNA molecule so that it can safety incorporate itself into the A site of the Ribosome to disruptits flow and "release" the protein and end translation.