Swimming at the 2016 Summer Paralympics – Women's 100 metre butterfly S10
The women's 100 metre butterfly S10 event at the 2016 Paralympic Games took place on 12 September 2016, at the Olympic Aquatics Stadium. Two heats were held. The swimmers with the eight fastest times advanced to the final.Heats
10:51 12 September 2016:
| Rank | Lane | Name | Nationality | Time | Notes |
| 1 | 5 | | | 1:11.22 | ' |
| 2 | 6 | | | 1:11.42 | ' |
| 3 | 2 | | | 1:12.89 | ' |
| 4 | 4 | | | 1:12.98 | ' |
| 5 | 7 | | | 1:13.81 | |
Heat 2
10:55 12 September 2016:
| Rank | Lane | Name | Nationality | Time | Notes |
| 1 | 4 | | | 1:04.37 | ' ' |
| 2 | 5 | | | 1:08.62 | ' |
| 3 | 3 | | | 1:09.39 | ' |
| 4 | 6 | | | 1:11.12 | |
| 5 | 2 | | | 1:13.40 | |
| 6 | 7 | | | 1:14.50 | |
Final
18:43 12 September 2016:
| Rank | Lane | Name | Nationality | Time | Notes |
| 4 | | | 1:02.65 | |
| 5 | | | 1:06.92 | |
| 2 | | | 1:08.77 | |
| 4 | 3 | | | 1:09.23 | |
| 5 | 6 | | | 1:09.73 | |
| 6 | 7 | | | 1:10.55 | |
| 7 | 8 | | | 1:11.92 | |
| 8 | 1 | | | 1:13.56 | |
