Swimming at the 2016 Summer Paralympics – Women's 50 metre butterfly S5
The women's 50 metre butterfly S5 event at the 2016 Paralympic Games took place on 10 September 2016, at the Olympic Aquatics Stadium. Two heats were held. The swimmers with the eight fastest times advanced to the final.Heats
10:11 10 September 2016:
| Rank | Lane | Name | Nationality | Time | Notes |
| 1 | 4 | | | 43.90 | ' |
| 2 | 5 | | | 46.13 | ' |
| 3 | 3 | | | 51.56 | |
| 4 | 7 | | | 52.54 | |
| 5 | 6 | | | 52.60 | |
| 6 | 2 | | | 56.23 | |
Heat 2
10:15 10 September 2016:
| Rank | Lane | Name | Nationality | Time | Notes |
| 1 | 5 | | | 47.73 | ' |
| 2 | 6 | | | 48.33 | ' |
| 3 | 3 | | | 49.78 | ' |
| 4 | 7 | | | 49.94 | ' |
| 5 | 4 | | | 50.63 | ' |
| 6 | 2 | | | 53.67 | ' |
| 7 | 1 | | | 1:18.68 | |
Final
18:03 10 September 2016:
| Rank | Lane | Name | Nationality | Time | Notes |
| 4 | | | 43.62 | |
| 1 | | | 45.67 | |
| 6 | | | 45.74 | |
| 4 | 5 | | | 45.82 | |
| 5 | 3 | | | 47.36 | |
| 6 | 8 | | | 47.51 | |
| 7 | 2 | | | 47.55 | |
| 8 | 7 | | | 50.89 | |
