Syndrome of subjective doubles


The []syndrome of subjective doubles is a rare delusional misidentification syndrome in which a person experiences the delusion that they have a double or Doppelgänger with the same appearance, but usually with different character traits, that is leading a life of its own. The syndrome is also called the syndrome of doubles of the self, delusion of subjective doubles, or simply subjective doubles. Sometimes, the patient is under the impression that there is more than one double. A double may be projected onto any person, from a stranger to a family member.
This syndrome is often diagnosed during or after the onset of another mental disorder, such as schizophrenia or other disorders involving psychotic hallucinations. There is no widely accepted method of treatment, as most patients require individualized therapy. The prevalence of this disease is relatively low, as few cases have been reported since the disease was defined in 1978 by George Nikolaos Christodoulou, a Greek-American Psychiatrist. However, subjective doubles is not clearly defined in literature, and, therefore may be under-reported.

Signs and symptoms

The symptoms of the syndrome of subjective doubles are not clearly defined in medical literature; however, there are some defining features of the delusion:

Similarities to other disorders are often noted in literature. Prosopagnosia, or the inability to recognize faces, may be related to this disorder due to the similarity of symptoms. Subjective doubles syndrome is also similar to delusional autoscopy, also known as an out-of-body experience, and therefore is occasionally referred to as an autoscopic type delusion. However, subjective doubles delusion differs from an autoscopic delusion: autoscopy often occurs during times of extreme stress, and can usually be treated by relieving the said stressor.
The syndrome of subjective doubles is usually accompanied by another mental disorder or organic brain syndrome, and may appear during or after the onset of the other disorder. Often, co-occurrence of subjective doubles with other types of delusional misidentification syndromes, especially Capgras syndrome, also occurs.
Several variations of the syndrome have been reported in literature:
The following case describes a patient who was diagnosed with psychotic depression, bipolar disorder, and the syndrome of subjective doubles:
Taken from Kamanitz et al., 1989:
The following case describes a patient who has been diagnosed with schizoaffective disorder along with multiple delusional misidentification syndromes :
Taken from Silva et al., 1994:
The following case describes a patient who has been diagnosed with chronic paranoid schizophrenia and reverse subjective doubles:
Taken from Vasavada and Masand, 1992:

Causes

Subjective doubles is commonly comorbid with other psychiatric illnesses, such as bipolar disorder or schizophrenia. The cause of the disorder is difficult to ascertain not only because of its rarity, but also due to the simultaneous presence of other disorders. While the physiological cause of the syndrome of subjective doubles has not been found, many hypotheses exist.
Some researchers believe that the syndrome of subjective doubles appears as a symptom of another disorder instead of a disorder of its own.
The syndrome of subjective doubles may also be related to substance dependence.
Another hypothesis states that subjective doubles is result of hyper-identification, linked to over-activity in certain areas of the brain, thereby causing the patient see familiar aspects of the self in strangers.
Some hypothesize that this delusion is a result of facial processing deficiencies, as it has seemingly similar symptoms of prosopagnosia; however, it must be noted that recognition of most faces is impaired in this delusion. Facial processing deficiencies also do not account for the occasion in which multiple doubles are reported.
Another hypothesis is that a "disconnection" between the right and left hemispheres may cause the delusional symptoms. This hypothesis relies heavily on the theory of lateralization of brain function, or left brain vs. right brain theory. In this hypothesis, the inability of the right hemisphere to "check" the left hemisphere causes the individual to succumb to delusions of self-awareness created by the left hemisphere.

Brain damage

One hypothesis is that brain dysfunction in the right hemisphere, temporal lobe, and/or bi-frontal lobes causes the delusion of subjective doubles. Physical damage resulting in the subjective doubles delusion often includes, but is not limited to, brain lesions or traumatic brain injury. Suspected organic causes of brain damage that may lead to subjective doubles include disorders such as epilepsy.
Because other mental illnesses are commonly co-morbid with subjective doubles syndrome, it is unknown whether these types of brain injuries are linked to the delusion or the additional mental illness. For example, right hemisphere brain damage is associated with schizophrenia, which is commonly reported with the delusion of subjective doubles.

Treatment

A widely accepted treatment for the syndrome of subjective doubles has not been developed. Treatment methods for this disease sometimes include the prescription of antipsychotic drugs, however, the type of drug prescribed depends on the presence of other mental disorders. Antipsychotic drugs such as risperidone, pimozide, or haloperidol may be prescribed to treat the underlying psychiatric illness.
In addition to drug therapy, interpersonal counseling has also been suggested as a method to ease relations between the patient and his/her suspected doubles. However, the relationship between the patient and his/her double is not always negative.

Prognosis

Recovery from this syndrome is situational, as some drug therapies have been effective in some individuals but not others. Patients may live in a variety of settings, including psychiatric hospitals, depending on the success of treatment. With successful treatment, an individual may live at home. In many of the reported cases, remission of symptoms occurred during the follow-up period.
This disorder can be dangerous to the patient and others, as a patient may interrogate or attack a person they believe to be a double. Inappropriate behavior such as stalking and physical or psychological abuse has been documented in some case studies. Consequently, many individuals suffering from this disorder are arrested for the resulting misconduct.

History

This disorder was first defined in 1978 by Greek psychiatrist George N. Christodoulou, M.D., Ph.D, FRCPsych. Although the symptoms of subjective doubles have been described before 1978, the disorder was not given a name until Christodoulou called it the syndrome of subjective doubles in the American Journal of Psychiatry. The article describes an 18-year-old female suffering from hebefreno-paranoid schizophrenia who believed that her next door neighbor had transformed her physical self into the patient's double. The syndrome of subjective doubles and its variants were not given the name delusional misidentification syndromes until 1981.
Doubles of the self have been reported in literature even before the syndrome was named by Christodoulou.
The first patient with symptoms of Capgras syndrome, another delusional misidentification syndrome, was reported in 1923 by Joseph Capgras and Jean Reboul-Lachaux. This patient, however, also experienced the delusion of subjective doubles, but the appearance of doubles of the self were not addressed until Christodoulou's article in 1978.

Controversy

Due to the rarity of this disorder and its similarities to other delusional misidentification syndromes, it is debated whether or not it should be classified as a unique disease. Because subjective doubles rarely appear as the only psychological symptom, it has been suggested that this syndrome is a rare presentation of symptoms of another psychological disorder. This syndrome is also not defined in the DSM-IV or ICD-10.
Additionally, some researchers use varying definitions of the syndrome. While most declare that the double is a physical copy that is psychologically independent, some refer to a definition of a double as being both physically and psychologically identical. This is also known as clonal pluralization of the self, another less common delusion that is grouped with the other delusional misidentification syndromes.

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