The base was located on Vinh Loc Island at the mouth of the Perfume River approximately 12 km northeast of Huế.
1967–70
The U.S. Navy established Tân Mỹ Naval Support Activity in 1967, the base comprised an LST ramp, Seabee base, docks and petroleum storage facilities together with a petroleum, oil and lubricants pipeline to Huế. The base was adjacent to the Eagle Beach rest and recreation facility. The base was initially defended by elements of the 3rd Marine Division. In February 1968 the U.S. Army's Task Force X-Ray assumed responsibility for base defense before handing control back to the 1st Marines in early March following the end of the Battle of Huế. The Navy Task Force 116, River Section 521 was based at Tân Mỹ before being moved north to Cửa Việt Base to form Task Force Clearwater. On 5 September 1968 the base was severely damaged by Typhoon Bess. A Loran-C station, designation SH-3 "Z" was established at Tân Mỹ in 1969 and operated by the United States Coast Guard. In March 1970 Tân Mỹ Naval Support Activity ceased operations and the base facilities were handed over to the U.S. Army Support Command.
On 22 March 1975 in the face of the PAVN offensive, the decision was made to abandon Huế and withdraw all South Vietnamese forces to an enclave around Danang. The plan was for the 147th Marine Brigade to withdraw to the Tân Mỹ Base where they would be picked up by Republic of Vietnam Navy ships. The base was soon swamped with Marines, soldiers and civilians seeking evacuation, however only smaller ships were able to dock at the base and ferry evacuees to larger ships offshore. Due to the overcrowding and the threat from the closing PAVN, the Marines moved further down the coast where two attempts were made to pick them up by LST over the next 2 days, however the LST could only approach to within several hundred feet of the shore forcing the Marines to attempt to swim out to the ship, in the end only approximately 600 of the 3000 Marines were evacuated to Danang.
Current use
The base is abandoned but the airfield and docks are still clearly visible on satellite images. On the ground, the airfield bitumen runway is still intact although overgrown with weeds, and the control tower is fully intact.