TAAR6


Trace amine associated receptor 6, also known as TAAR6, is a protein which in humans is encoded by the TAAR6 gene.

Function

TAAR6 belongs to the trace amine-associated receptor family. Trace amines are endogenous amine compounds that are chemically similar to classic biogenic amines like dopamine, norepinephrine, serotonin, and histamine. Trace amines were thought to be 'false transmitters' that displace classic biogenic amines from their storage and act on transporters in a fashion similar to the amphetamines, but the identification of brain receptors specific to trace amines indicates that they also have effects of their own.
Computational modeling suggests TAAR6 can bind to the foul smelling compounds produced by rotting flesh, putrescine and cadaverine.

TAAR6 knockout mice have some differences in behaviour, so this gene can have some functions in CNS.