He was first known in his high school days as a prospect while playing for Xavier School and leading his team to many victories. Scouts were already eyeing him until he chose to play with the De La Salle Green Archers when he entered college. He did not live up to the expectations in his rookie year, averaging 1 point and 1 assist. He had minimal contributions in the 2004 UAAP championship. In 2006 they were suspended for ineligible players. Following their suspension La Salle joined the Filoil Flying V Cup;Tang stunned all critics with his vastly improved game averaging 17 points, 5 rebounds and 4 assists. In the UAAP he led the archers against 14-0 UE warriors to win the Championship. He averaged 13 points, 4 rebounds and 4 assists in the playoffs.
After leading the Archers in the Season 70 championship, he joined the Harbour Centre in the PBL. He had his career high on the opening game with 26 points against the RP Team. At the season's finals, his team found themselves the "underdog" against Hapee, a team led by Fil-Am Gabe Norwood. He and Solomon Mercado led the team to an incredible come from behind-win against Hapee. Tang was adjudged the PBL Finals MVP for his performance and was included in the Mythical Second Team for the season. He also led the league in three-point shooting with 2.1 conversions per game and with a 35% shooting clip.
PBA
On August 31, 2008, at the PBA Draft at Market! Market!, Tyrone was drafted by the Welcoat Dragons as the twelfth overall. He announced his retirement on August 25, 2015 to focus on his business career.
PCBL
However, Tang came out of retirement and signed as a player of the new team, Mighty Sports in the Pilipinas Commercial Basketball League in 2016.
International career
Tang was also part of the RP Team that was the runner-up in the SEABA tournament. Tang led his team in scoring averaging 18 points per game. Though they ended up losing to Indonesia, it was their only loss in the tournament.
Coaching career
On November 23, 2016, Spin.ph reported that Tang will be appointed as the head coach of the CSB Blazers in the NCAA, following the resignation of former head coach Gabby Velasco at the end of Season 92 men's basketball tournament due to dismal performance of the team, where they only won a single game out of 18 outings.