Table of medication secreted in kidney
This is a table of medications that are secreted in the kidney.
Acid medication are, because of pH partition, secreted to a higher extent when urine is basic. In the same way, basic medications are secreted to a higher extent when urine is acidic.
Medication | Location | Acid or base | anion or cation | Percentage excreted |
para-aminohippurate | proximal tubule | Acid | anion | |
furosemide | proximal tubule | Acid | anion | 100-75 |
glucuronic acid-conjugates | proximal tubule | Acid | ||
glycine conjugates | proximal tubule | Acid | ||
indometacin | proximal tubule | Acid | anion | |
methotrexate | proximal tubule | Acid | 100-75 | |
penicillin | proximal tubule | Acid | anion | 75-50 |
probenecid | proximal tubule | Acid | anion | |
sulphate conjugates | proximal tubule | Acid | ||
thiazide diuretics | proximal tubule | Acid | ||
uric acid | proximal tubule | Acid | ||
amiloride | proximal tubule | Base | cation | |
dopamine | proximal tubule | Base | ||
histamine | proximal tubule | Base | ||
mepacrine | proximal tubule | Base | ||
morphine | proximal tubule | Base | cation | |
pethidine | proximal tubule | Base | ||
quaternary ammonium compounds | proximal tubule | Base | ||
quinine | proximal tubule | Base | cation | |
5-hydroxytryptamine | proximal tubule | Base | ||
triamterene | proximal tubule | Base | ||
gentamicin | 100-75 | |||
atenolol | 100-75 | |||
digoxin | 100-75 | |||
cimetidine | cation | 75-50 | ||
tetracycline | 75-50 | |||
neostigmine | 75-50 | |||
propantheline | ~50 | |||
tubocurarine | ~50 | |||
acetazolamide | proximal tubule | anion | ||
chlorothiazide | proximal tubule | anion | ||
saccharin | proximal tubule | anion | ||
salicylate | proximal tubule | anion | ||
atropine | proximal tubule | cation | ||
NMN | proximal tubule | cation | ||
paraquat | proximal tubule | cation | ||
procainamide | proximal tubule | cation | ||
tetraethylammonium | proximal tubule | cation | ||
chlorpromazine | proximal tubule | cation |