The show features Milonakis as well as a supporting cast made up of his actual neighbors and people from the Lower East Side, Manhattan neighborhood where the show originally took place. There is no plot and the comedy in the sketches tends to be absurdist and silly. Despite its time slot and intended audience, the content is rated TV PG. There are often animated segments, and often man-on-the-street segments. The last sketch of the show usually involves a celebrity guest. In the third and final season, Milonakis moved to Los Angeles to be with his now famous pet turtle, Herbie. His best friend, Ralphie, sneaks along and moves with him. Ralphie made their old friends into household items so they could be with Andy too. However, they played significantly smaller roles than in the prior two seasons.
Series history
The first two seasons, filmed in New York City, each consisted of eight episodes. The main cast consisted of Andy, Ralphie, Larry and Rivka. Billy, who was seen in only a few bits in the first season, became a cast member for season two. Andy was always seen in his trademark red plaid button-down shirt for these two seasons. The third season consisted of six episodes. Andy moves to Los Angeles, and begins wearing a blue plaid button-down shirt, given to him by Ralphie, who had been wearing it under his arm "to stop the sweat." Ralphie is the only original cast member to join Andy for season three, but is able to bring along the remaining cast as household items. He turned Larry into a can opener, mounted Rivka's head and put Billy's soul on his shoe. Season two introduced a cartoon show-within-a-show called "The Lower East Side Dysfunctional Monster Gang Squad Family Cartoon Show." For season three, the title remained the same, albeit adding "In L.A." at the end. Andy provided the voices of Handsome Pig, Vicious Critter and Baby Dracula. Ralphie voiced Hairmouth, Rivka voiced Eyemouth Susie, Larry voiced Acid Reflux Charlie and Billy voiced Not-So-Human Stick. Season three also introduced a new theme song, with Andy rapping about his move to Los Angeles, while making references to lines from the original theme song.