The New York Times Fiction Best Sellers of 2019
This is a list of adult fiction books that topped The New York Times Fiction Best Seller list in 2019, in the Combined Print & E-Book Fiction category.
The most frequent weekly best seller of the year was Where the Crawdads Sing by Delia Owens with 25 weeks at the top of the list.
| Date | Book | Author |
| January 6 | The Reckoning | John Grisham |
| January 13 | The Long Road to Mercy | David Baldacci |
| January 20 | Verses for the Dead | Douglas Preston and Lincoln Child |
| January 27 | Turning Point | Danielle Steel |
| February 3 | Where the Crawdads Sing | Delia Owens |
| February 10 | Where the Crawdads Sing | Delia Owens |
| February 17 | Where the Crawdads Sing | Delia Owens |
| February 24 | Connections in Death | J. D. Robb |
| March 3 | Where the Crawdads Sing | Delia Owens |
| March 10 | Where the Crawdads Sing | Delia Owens |
| March 17 | Where the Crawdads Sing | Delia Owens |
| March 24 | Where the Crawdads Sing | Delia Owens |
| March 31 | Where the Crawdads Sing | Delia Owens |
| April 7 | Where the Crawdads Sing | Delia Owens |
| April 14 | Where the Crawdads Sing | Delia Owens |
| April 21 | Where the Crawdads Sing | Delia Owens |
| April 28 | Where the Crawdads Sing | Delia Owens |
| May 5 | Redemption | David Baldacci |
| May 12 | Neon Prey | John Sandford |
| May 19 | 18th Abduction | James Patterson and Maxine Paetro |
| May 26 | Where the Crawdads Sing | Delia Owens |
| June 2 | Where the Crawdads Sing | Delia Owens |
| June 9 | Where the Crawdads Sing | Delia Owens |
| June 16 | Where the Crawdads Sing | Delia Owens |
| June 23 | Where the Crawdads Sing | Delia Owens |
| June 30 | Where the Crawdads Sing | Delia Owens |
| July 7 | Summer of '69 | Elin Hilderbrand |
| July 14 | Where the Crawdads Sing | Delia Owens |
| July 21 | Where the Crawdads Sing | Delia Owens |
| July 28 | Under Currents | Nora Roberts |
| August 4 | The New Girl | Daniel Silva |
| August 11 | One Good Deed | David Baldacci |
| August 18 | Where the Crawdads Sing | Delia Owens |
| August 25 | Where the Crawdads Sing | Delia Owens |
| September 1 | Where the Crawdads Sing | Delia Owens |
| September 8 | Where the Crawdads Sing | Delia Owens |
| September 15 | A Better Man | Louise Penny |
| September 22 | Vendetta in Death | J. D. Robb |
| September 29 | The Institute | Stephen King |
| October 6 | The Institute | Stephen King |
| October 13 | The Water Dancer | Ta-Nehisi Coates |
| October 20 | Bloody Genius | John Sandford |
| October 27 | The 19th Christmas | James Patterson and Maxine Paetro |
| November 3 | The Guardians | John Grisham |
| November 10 | The Night Fire | Michael Connelly |
| November 17 | Blue Moon | Lee Child |
| November 24 | Blue Moon | Lee Child |
| December 1 | Twisted Twenty-Six | Janet Evanovich |
| December 8 | A Minute to Midnight | David Baldacci |
| December 15 | The Rise of Magicks | Nora Roberts |
| December 22 | The Guardians | John Grisham |
| December 29 | Where The Crawdads Sing | Delia Owens |