Noguchi was born in Fukuoka Prefecture, raised in Yokosuka and graduated from Tokyo's Nippon Medical School in 1951 before interning at The University of Tokyo School of Medicine Hospital. Shortly thereafter he emigrated to the United States. He then served a second internship at Orange County General Hospital and a series of residencies at Loma Linda University School of Medicine, and Barlow Sanatorium in Los Angeles. He was appointed a deputy coroner for Los Angeles County in 1961. In 1967, he became Chief Medical Examiner-Coroner for the County of Los Angeles, replacing his mentor Theodore Curphey. As CME, Noguchi came to public attention for a series of autopsies; which he performed or supervised on a range of celebrities and public figures that included Albert Dekker, Robert F. Kennedy, Sharon Tate, Janis Joplin, Inger Stevens, Gia Scala, David Janssen, William Holden, Natalie Wood, Marilyn Monroe, and John Belushi. His autopsy of Kennedy concluded that the fatal shot was fired into the back of Kennedy's head, behind the right ear, from an upward angle, and from a distance of no more than 0.5 to 3 inches away. Such a finding has given rise to conspiracy theories regarding the assassination, as no witnesses reported seeing the convicted assassin, Sirhan Sirhan, any closer to Kennedy than 1 meter away and in a position to fire such a shot. Noguchi himself points out in his memoir Coroner that he has never officially ruled that Sirhan fired the fatal shot. He developed a high profile as CME, and was often accused of speaking too freely to the media, particularly following the November 1981 deaths of William Holden and Natalie Wood, which, along with moonlighting and alleged mismanagement, led to his demotion from coroner to physician specialist in 1982. He was later appointed Chief of Pathology at the University of Southern California and then as Administrative Pathologist for Anatomic Pathology services at the USC Medical Center. Noguchi was appointed professor by both the University of Southern California and UCLA. He is a past president of the American National Association of Medical Examiners. In 1999 he was honored by the Emperor of Japan who awarded him the Order of the Sacred Treasure for his "outstanding contributions to Japan in the area of forensic science". He retired the same year. , Noguchi is the president of World Association for Medical Law, which is a medical body founded in 1967 to encourage the study of health law, legal medicine, and bioethics.
Publications
Coroner, 1983. A best selling memoir written with Joseph DiMona.
Coroner at Large 1985. A book about historical coroners and famous deaths.
Unnatural Causes, 1988. A detective novel written with Arthur Lyons.
Physical Evidence, 1990. A detective novel written with Arthur Lyons.
He appeared as himself in the film Faces of Death.
In 2000, Noguchi appeared in Michael Kriegsman's autopsy-related documentaries, "Autopsy: Through the Eyes of Death's Detectives"; and "Autopsy: Voices of Death", wherein Noguchi takes the viewer through a complete autopsy.
He is said to have been the inspiration for the TV series Quincy, M.E., which starred Jack Klugman.
