Smith entered the University of Edinburgh in October 1812, and in November took over the Unitarian congregation meeting in Skinners' Hall, Canongate, which had stayed together without a minister since the death in 1795 of James Purves; he raised the attendance sharply. In June 1813 he began a course of fortnightly evening lectures on universal restoration; these were published in 1816 and made him a literary reputation. Also in 1813 he founded the Scottish Unitarian Association, with James Yates. In 1816 he took his M.D. degree, and began to practice at Yeovil, Somerset, also becoming minister at a chapel in that town, but moved in 1820 to London, devoting himself mainly to medicine.
Smith died in Florence in 1861 and is interred there in the English Cemetery of Florence, his tombstone, an obelisk with a cameo portrait, was sculpted by Joel Tanner Hart. His daughter Emily, who died in 1872, is buried beside him.
Bentham dissection
Southwood Smith was a dedicated utilitarian, and a close friend of Jeremy Bentham. He had a particular interest in applying his philosophical beliefs to the field of medical research. In 1827 he published The Use of the Dead to the Living, a pamphlet which argued that the current system of burial was a wasteful use of bodies that could otherwise be used for dissection by the medical profession. On 9 June 1832, Southwood Smith carried out the highly controversial public dissection of Jeremy Bentham at the Webb Street School of Anatomy in London. In a speech before the dissection, Southwood Smith argued that Smith's lobbying helped lead to the 1832 Anatomy Act, the legislation which allowed the state to seize unclaimed corpses from workhouses and sell them to surgical schools. While this act is credited with ending the practice of grave robbery, it has also been condemned as discriminatory against the poor.
Works
In 1830 Smith published A Treatise on Fever, which became a standard authority on the subject. In this book he established a direct connection between the impoverishment of the poor and epidemic fever. The underlying theory opposed contagion as a mechanism of spread of disease, and postulated no pathogen that was airborne; it argued that the exclusion of "pure air" could suffice to create mortal disease.
Family
Smith was twice married, and left by his first marriage two daughters Caroline and Emily; by his second marriage an only son, Herman. Miranda and Octavia Hill were his granddaughters, among the five daughters of Caroline who married James Hill, merchant in 1835, and as Caroline Southwood Hill was known as a writer and educationalist. His other daughter was Emily. Smith had separated from his second wife by the end of the 1830s, and then lived for the rest of his life with the artist Margaret Gillies. Along with his son Herman and daughter Emily they visited Wisbech in June 1836 and dined with Caroline and the actor William Macready, who was appearing as Hamlet in the Georgian Angles Theatre owned by James and Caroline. They also owned a school they built in front of the theatre. Following his son in law James Hill's second bankruptcy in 1840, his three year-old grand daughter Gertrude Hill came to live with him. In the 1861 census the household lived at Heath House, Weybridge and consisted of Thomas Smith 72, Mary Gillies 62, Margaret Gillies 56, his son Herman Smith 40, wine merchant, his granddaughter Gertrude Hill, 23 lady, and a cook and a housemaid.