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Thyronamine
Thyronamine
refers both to a
molecule
, and to
derivatives
of that molecule: a
family
of
decarboxylated
and
deiodinated
metabolites
of the
thyroid hormones
thyroxine
and
3,5,3'-triiodothyronine
.
Types
The group includes:
Thyronamine
3-Iodothyronamine
, which is the most
notable
one as it is a
trace amine
found in
the nervous system
. It is a possible
candidate
for the
natural
ligand
of the
trace amine-associated receptor
TAAR1
, an
intracellular
G protein-coupled receptor
3,5-Diiodothyronamine
3,5,3'-Triiodothyronamine