McCarthy was born on 15 July 1888 in Kinsale, Ireland. He signed on the Endurance as an able seaman, and participated fully in the dangers and privations of the Weddell Sea, particularly after the Endurance sank and the ship's company and shore party were marooned on a nearby ice floe. Later, the ship's company and shore party were forced to take to lifeboats, and the seamanship of the ABs became a decisive element in the survival of the entire company. Expedition commander Ernest Shackleton was impressed by McCarthy's skill during the survival journey from the northern Weddell Sea to Elephant Island, and so when the expedition leader decided to relaunch the bestlifeboat into the open Southern Ocean, with the goal of contacting potential rescuers in South Georgia, McCarthy was one of the five men he chose to accompany him. The sixteen-day voyage of the James Caird in April–May 1916 became a classic story of human endurance, and the boat's navigator, Frank Worsley, offered fervent and repeated praise to McCarthy for his services in keeping the boat afloat and helping to ensure the survival of the party. When the James Caird, in a sinking condition, made landfall on South Georgia's uncharted southern coast, two of the six men of the company were physically unfit for further service. Shackleton and his men turned over the boat and made it into a primitive shore shelter, which they called Peggotty Camp. Three of the men—Tom Crean, Worsley, and Shackleton himself—crossed the icy island to finalise the rescue, while the other three, the ageing carpenter Henry McNish and incapacitated seaman John Vincent, briefly remained at the camp under McCarthy's informal leadership. The island crossing was successful and the party was reunited after less than forty-eight hours. Soon McCarthy found himself heading northward. Having successfully participated in his own rescue, his part in the expedition was over. Upon making landfall in the British Isles, McCarthy found his country fighting World War I. He joined the Royal Navy Reserve as a leading seaman. In these duties he was assigned to man a deck gun on the S.S. Narragansett, an oil tanker. On 16 March 1917, this vessel was torpedoed and sunk with all hands in the Western Approaches. McCarthy, aged 28, was the first member of the Weddell Sea party of the Imperial Trans-Antarctic Expedition to die.