Wilkinson made his acting debut in 1976 and worked on several British television series, most notably the mini-series First Among Equals. He first gained critical acclaim with his appearance as Mr Pecksniff, in the BBC's 1994 adaptation of Martin Chuzzlewit. Wilkinson made only the occasional film, including a brief appearance in 1995's Sense and Sensibility and a villain in The Ghost and the Darkness. After becoming part of the ensemble cast of the comedy-drama The Full Monty in 1997, a role which earned him a BAFTA, he began to take film roles more frequently, including supporting roles in Oscar and Lucinda, Wilde, Shakespeare in Love, and The Patriot. He also starred with Jackie Chan in the 1998 film Rush Hour, as the evil British Ambassador/Juntao. His portrayal of Matt Fowler, in Todd Field's In the Bedroom, received international praise from critics. For the role, he was named Best Actor of the Year by the New York Film Critics' Circle, and went on to be nominated for the Academy Award for Best Actor. That success was followed up by Eternal Sunshine of the Spotless Mind, Normal, The Exorcism of Emily Rose, Batman Begins, and Separate Lies. In 2007, Wilkinson played Arthur Edens, an attorney with bipolar disorder, in Michael Clayton and garnered much critical acclaim and a nomination for the Academy Award for Best Supporting Actor. The same year, he played an uncle planning for murder in Woody Allen's Cassandra's Dream, and played opposite Billy Crudup as children's book writing partners in Dedication. In 2008, Wilkinson portrayed American polymath Benjamin Franklin in the HBO mini-series John Adams. In the HBO film, Recount, Wilkinson portrayed American political adviser and lawyer, James A. Baker, in Baker's capacity as Chief Counsel to George W. Bush during the 2000 U.S. Presidential Election, receiving an Emmy Award for the former and a nomination for the latter. He also received a Golden Globe Award and Screen Actors' Guild Award nomination for his role in John Adams. He also portrayed Friedrich Fromm, Commander in Chief of the German Reserve Army, alongside Tom Cruise in the 2008 World War II thriller Valkyrie. Wilkinson starred in the horror comedy Burke and Hare, which is directed by John Landis. He portrayed a covert CIA agent in Roman Polanski's The Ghost Writer. He played another historical character, Joseph P. Kennedy Sr., in the 2011 television miniseries The Kennedys, for which he was nominated for the Primetime Emmy Award for Outstanding Supporting Actor in a Miniseries or a Movie. He and his wife portrayed husband and wifeJoe and Rose Kennedy. Earlier that year, he appeared in The Green Hornet and . In 2014 Wilkinson portrayed the 36th President of the United States Lyndon B. Johnson in the historical drama filmSelma.
Personal life
Wilkinson lives in North London with his wife, actress Diana Hardcastle. They were married on 5 January 1988 and have two daughters together, Alice and Molly.