Cannon first bought a guitar at age 22. He played reggae music before playing blues. Among the influences he has named are Albert Collins, B.B. King, Freddie King, Buddy Guy and Jimi Hendrix. Cannon played guitar with Tommy McCracken, Wayne Baker Brooks, L.V. Banks and Joanna Connor beginning in 1996. He started his own band, The Cannonball Express in 2001. He recorded My Woman, Leaving Mood and John The Conqueror Root. The third album was nominated for a Blues Music Award as Rock BluesAlbum of the Year in 2013. He signed with Alligator Records in 2015. His Alligator Records debut, The Chicago Way, co-produced by Cannon and Alligator Records president Bruce Iglauer, was released on February 26, 2016. Cannon drives a Chicago Transit Authority bus during the day and performs at night, on weekends and during vacation breaks. Cannon has performed at the Chicago Blues Festival nine times. He headlined in 2015. He has also performed in many United States and European cities. His overseas tours include Mexico, South Africa, Armenia, France and Netherlands, France and Spain and Sweden, France, Spain, Belgium, Netherlands and Luxembourg. His UK debut came at the Edinburgh Blues Club Voodoo Rooms in 2017. His daughter, Gayun Cannon, is also a talented, multi-instrumentalist who goes to Whitney M. Young Magnet High School. Blues Matters said, "Toronzo is the real deal. Blistering guitar and inventive songs: jealousy, double-crossing, knives and harnd grenades... Chicago style." The Chicago Tribune said, “Chicago-based Toronzo Cannon, who performed for the first time as a festival headliner, made the most of this opportunity to win over a new audience. His extroverted guitar style sounded especially compelling when he closely engaged with keyboardist Ronnie Hicks' sturdy chord changes. Cannon also has a forceful singing voice, whether narrating an original murder ballad or on his upbeat "Sweet Sweet Sweet." The Chicago Sun-Times said, “The Bridgeport resident was immersed in the world of blues by hanging around Theresa’s Lounge. Today he’s one of Chicago’s new greats." The Chicago Reader said, “Local singer and guitarist Toronzo Cannon shows off his impressive range on 2013's John the Conquer Root, tackling full-band soul, airy acoustic ballads, and rough-and-tumble biker-bar rock 'n' roll. Cannon excels when he lets his ax take the lead: on the title track, for instance, he doles out slow, shimmying riffs and smoldering licks. Blues & Rhythm said, “Without sounding like I'm going over the top with praise, this release is terrific and top heavy with superb musicianship and quality material and is worthy of any blues lover's attention. It also highlights the cream of the next generation of blues musicians starting to make their names on the Chicago blues scene." His 2016 album, The Chicago Way was nominated for a Blues Music Award in 2017 as Album of the Year.
