He has toured the UK supporting both Stewart Lee and Russell Brand and made appearances at the Edinburgh Fringe. He is a founder member and co-host of the comedy cabaret Kool Eddy's in London, which he also took to the Edinburgh Fringe festival. In 1999 Lock appeared in Number One Show with Daniel Kitson and Andrew Maxwell at The Gilded Balloon. In 2006 he performed a one-off hour of stand-up Edinburgh Fringe show, When I was a Little Girl – The Very Best of Trevor Lock, at the Gilded Balloon Teviot Wine Bar, Edinburgh and appeared in Cloud Cuckooland, a work-in-progress for a forthcoming BBC Radio show with Russell Brand and Matt Morgan, at the Smirnoff 'Underbelly', Cowgate. Trevor also supported Russell Brand on a number of dates for his stand-up show Shame. In November 2007 Trevor addressed the Oxford Union on The Meaning of Life in the same week as the British National Party. He disproved Descartes' maxim "Cogito ergo sum" by tipping a glass of water over his head, horrifying the front row of the audience. In 2009, Trevor Lock performed a warm up show for the Edinburgh Fringe Festival at a fundraiser for Boxmoor Cricket Club. He had two shows in the 2009 Edinburgh fringe; a stand up show called Some Kind of Fool and a play titled The One and the Many Lock presents a live comedy night 'Trevor Lock's Philosophy Society' at the Ku Bar in Lisle Street near Leicester Square. In early 2011 Lock revealed plans to tour the UK with a series of gigs held exclusively in people's livingrooms called Live in My Living Room.
Radio
Lock appeared with Russell Brand and Matt Morgan on Brand's Saturday night BBC Radio 2 show, and appeared alongside the pair on Brand's Sunday morning show on BBC 6 Music. He was often referred to by the nickname 'Cocky Locky'. Trevor was often teased by his co-hosts for supposedly being cruel to animals, having told several stories involving a boot coming through a ceiling and lying or inventing anecdotes. The first of these themes came after a show based on the theme, "What Have I Done To Deserve This?" in which Lock told a story of being caught accidentally drowning a rodent by a vicar. Brand and Morgan would regularly deride Lock about this and other anecdotes, exaggerating them for comedic purposes. The show also featured "Trevor's Sonic Enigma" which Brand and Morgan dubbed "Trevor done a Noise". This was meant to be a short clip of sound effects and voices which would enable listeners to guess the title of a song. These enigmas were notable for being misleading and confusing as well as very long. Winners were invited to join the presenters in the studio the next week. Another regular item was "Challenge Trevor" in which Trevor was set a list of undesirable challenges by the listeners. These went from eating lemons to serenading Noel Gallagher with an Oasis song in Lock's Elvis Presley voice. A running joke was that Brand would shout at Lock: "Eat your fudge!". This catchphrase stemmed from a particular broadcast when Brand presented him with large quantities of the foodstuff. The catchphrase was continued for the duration of the 6 Music show, and people went as far to shout out the phrase at his stand-up shows. When the trio went to Edinburgh in 2006, Lock was arrested for an alleged sexual assault of a 20-year-old student at Brand's flat on 28 August. The case was not pursued, and although Lock returned to the 6 Music show in October 2006, Brand noted: "It was the beginning of the end of our relationship really, because it's hard to recover from that kind of thing." On 10 March 2007, it was announced that he had left the show, by that time on Radio 2, to pursue his own projects, reportedly his own pilot for BBC 6 Music. On Saturday 12 October 2013 before a performance of Brand's 'Messiah Complex' at The Usher Hall in Edinburgh, Brand met Lock at The Raddison Hotel. There, Brand finally apologised to Lock, saying 'You should never have got the blame for all that'.
Television
Between 1998 and 1999, Lock regularly appeared in the Lee and Herring BBC Sunday lunchtime show, This Morning With Richard Not Judy. He was mocked weekly by Stewart Lee for having a "small face", but was not allowed to speak as this would mean him having to be paid more. He also appeared in two episodes of Time Gentlemen Please, once in the first series in 2000, and once in the second series in 2002. In 2003, he appeared in BBC3's Brain Candy. Lock played a variety of roles in Channel 4's Star Stories including Michael Parkinson, Billy Bob Thornton, Glenn Hoddle, Emilio Estevez and Ant McPartlin.
