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Trioxifene
Trioxifene
, or as the
salt
trioxifene
mesylate
, is a
selective estrogen receptor modulator
with
competitive binding
activity
against
estradiol
for the
ERα
and
antagonistic
activity against ERα-mediated
gene expression
, that was under
preclinical
and
clinical development
by
Eli Lilly and Company
for
breast cancer
and
prostate cancer
, but was
abandoned
.