Naoki Kazumi is a boy whose parents died in an accident five years ago, and his memory went along with it. Since he had nowhere else to go, he lives with his cousin Matsuri Shibugaki and her parents. Every morning before school, he is awakened by his childhood friend, Honami Fujieda, who keeps telling him that he is not a child anymore, but still comes to wake him up. These usual, ordinary days seem to stretch on forever, until one day up on the school's rooftop, while Naoki is taking a peaceful nap, out of nowhere, a girl falls out of the sky. This girl, called Mikoto Amagasaki, comes from 100 years in the future, and she went back in time with the intention of finding her brother. When Mikoto sees Naoki, she mistakes him for her brother.
A manga for Tsuki wa Higashi ni Hi wa Nishi ni, illustrated by Takeda Mika, began serialization in Dengeki G's Magazine on January 27, 2005. The manga was published by ASCII Media Works, and Dengeki Comics. Only one volume was published. An anthology comic consisting of four panel comic strips, has also been publicized, published under and issued by Majiku Comics on January 29, 2004. A novel series for Tsuki wa Higashi ni Hi wa Nishi ni was written by Okada Runa and published by Harvest. The first volume was published on March 25, 2004, and volume two and three were published on April 25, 2004 and May 25, 2004. A light novel called Tsuki wa Higashi ni Hi wa Nishi ni: Tōhonseisō Sukūruraifu was published by Gakken on December 25, 2004, and written by Kano Kiichi. The light novel contains a short stories collection featuring the heroines. It was serialized in the Megami Magazine.
Drama CDs
Several drama CDs based on the game have been produced by Geneon Universal. Tsuki wa Higashi ni Hi wa Nishi ni's first drama CD was released on February 25, 2004. A second drama CD was released on April 23, 2004, entitled Tsuki wa Higashi ni Hi wa Nishi ni - Groovin' White Vacation. The first volume of another drama CD was released on October 22, 2004, the second volume was later released on November 25, 2004. The third volume was released on December 22, in the same year.
Anime
An anime adaptation was produced by RADIX, and directed by Mitsuhiro Tōgō and Shousei Jinno. The anime was based on Honami scenario of PC version, and contained twelve episodes and a special episode which mainly aired on Japanese Association of Independent Television Stations between June and September 2004. Four DVDs were released between October 22 and December 12, 2004 and additional four episodes based on Mikoto scenario were contained in volume four.