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U-69,593
U-69,593
is a
drug
which
acts
as a
potent
and
selective
κ
1
-opioid
receptor agonist
. In
animal studies
it has been
shown
to
produce
antinociception
,
anti-inflammation
,
anxiolysis
,
respiratory depression
, and :wikt:diuresis|diuresis, while having little
effect
on
gastrointestinal motility
. It also inhibits the
peripheral
, though not
central
secretion
of
oxytocin
and
vasopressin
in
rats
.