UBTF
Nucleolar transcription factor 1 is a protein that in humans is encoded by the UBTF gene.Function
Upstream binding factor is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1. Two UBF polypeptides, of 94 and 97 kD, exist in the human. UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes.Interactions
UBTF has been shown to interact with:
