USP1
Ubiquitin carboxyl-terminal hydrolase 1 is an enzyme that in humans is encoded by the USP1 gene.
This gene encodes a member of the ubiquitin-specific processing family of proteases that is a deubiquitinating enzyme with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins.
The protein specifically deubiquitinates a protein in the Fanconi anemia DNA repair pathway. Alternate transcriptional splice variants have been characterized.
