This municipal museum was designed by the architects Rafael Moneo and Enrique de Teresa with the help of Francisco Romero and Juan Jose Echevarria. The museum is to the south west of the city on the right bank of the River Pisuerga with an emblematic footbridge it is seen as a symbol of the city and for the region of Castilla y León.
North Plaza
was born in the city and after qualifying as a doctor went on to investigate what are now called neurons. He was responsible for discovering microglia. There is a statue of him outside. Also in the plaza is a statue of Albert Einstein sitting at a bench with his calculations. The plaza also has a weather station.
Lobby
The permanent exhibition in the lobby includes two cars. The fastest is a Williams-RenaultFormula 1 car that won the constructors prize. The earlier car is the only car that has been declared of cultural interest to Spain. This is a Renault 4/4 which were constructed in the city at the FASA plant. The lobby has temporary exhibitions and also displays local meteorites and a large model of the DNA molecule. Besides an area dedicated to Castilla y León inventions and inventors there is an eleven metre high 80 kg Foucault Pendulum as well as a display of Louis Pasteur's work improving wine production.
First Floor
The first floor has a number of interactive displays. One explains the different ways of generating electricity whilst a model of the town shows the cycle of water usage. A large display illustrates Mendeleev and his periodic table whilst another has a three eyed guide called Tripos who explains aquatic life.
The River House was first opened in 2007, but it has since been extended to allow more aquariums, terrariums and interactive displays. The house exploits the museum's location on the banks of the River Pisuerga to explain geography and ecology with reference to the city of Valladolid. The entire ecosystem is illustrated and includes examples of the important species of fish, amphibians and shellfish that should thrive in the region's rivers. Displays illustrate metamorphosis of frogs and toads. The water cycle is explained and its importance in a time of climate change.
Planetarium
The museum claims the honour of having the first digital planetarium in Spain. The 11 metre dome is inclined at an angle of 15 degrees and s used to display astronomical animations of the solar system, galaxies and stars which are described by resident astronomers. The picture on the dome is created by 11.5 million pixels created by six aligned projectors.