Verocay body


Verocay bodies were first described by Uruguayan neuro-pathologist José Juan Verocay in 1910. It is a required histopathological finding for diagnosing Schwanommas. Verocay Bodies are a component of Antoni A which are the dense areas of schwannomas located between palisading spindle cells found in neoplasms. Two nuclear palisading regions and an anuclear zone make up 1 Verocay Body.
Naming History:
Originally Verocay bodies were called 'neuromas', a term coined by Louis Odier in 1803. The name changed to ‘neuro-fibroma’ under Von Recklinghausen and later in 1935 to ‘neurilemmomas’ curtesy to Arthur Purdy Stout. When Harkin and Reed coined the term 'schwannoma' in 1968, Verocay bodies received its present-day name.
H/P features:
1.Eosinophilic acellular area due to overexpression of lamins.
2.Consisting of reduplicated basement membrane and cytoplasmic processes.