Vinyltestosterone


Vinyltestosterone is a synthetic anabolic–androgenic steroid that was never marketed. However, two 19-nortestosterone derivatives of vinyltestosterone, norvinisterone and norgesterone, have been marketed. They are used as progestins for female hormonal contraception, rather than as AAS.
Vinyltestosterone is a relatively weak AAS. In one study, it showed approximately one-third and one-fifth of the respective androgenic and anabolic activity of other AAS such as nandrolone, methyltestosterone, and ethyltestosterone in castrated male rats, whereas ethisterone showed almost no androgenic and anabolic activity. Additionally, in women with metastatic breast cancer, vinyltestosterone was found to be ineffective in treating the disease and produced little or no virilization in the women at a dosage of 100 mg intramuscularly three times per week.