WIPI protein family
The WIPI protein family is an evolutionarily conserved family of proteins. WIPI proteins contain a WD repeat domain that folds into a 7-bladed beta-propeller that functions in autophagy, and contain a conserved motif for interaction with phospholipids.
Members of this family include:
Protein | Gene | Aliases | Yeast |
WIPI-1 | WIPI1 | WIPI49, FLJ10055 | Atg18 |
WIPI-2 | WIPI2 | Svp1a, DKFZP434J154 WIPI49-like protein 2 | Atg21 |
WIPI-3 | WDR45L | 628 protein, WIPI49-like protein | |
WIPI-4 | WDR45 | JM5 protein, WDRX1 |